The RAS/MAP kinase and the RAS/PI3K/AKT pathways play a key role in the regulation of
proliferation, differentiation and survival. The induction of these pathways depends on …

Fibroblast growth factors (FGFs) and their receptors control a wide range of biological
functions, regulating cellular proliferation, survival, migration and differentiation. Although …

Amplification of fibroblast growth factor receptor 1 (FGFR1) occurs in∼ 10% of breast
cancers and is associated with poor prognosis. However, it is uncertain whether …

FGFs (fibroblast growth factors) and their receptors (FGFRs) play essential roles in tightly
regulating cell proliferation, survival, migration and differentiation during development and …

Breast cancer is a complex and heterogeneous disease, comprising multiple tumor entities
associated with distinctive histological patterns and different biological features and clinical …

Triple negative breast cancers (TNBCs) have a relatively poor prognosis and cannot be
effectively treated with current targeted therapies. We searched for genes that have the …

The fibroblast growth factor receptors (FGFR) play essential roles both during development
and in the adult. Upon ligand binding, FGFRs induce intracellular signaling networks that …

We recently developed a user-friendly web-based application called bc-GenExMiner
(http://bcgenex. centregauducheau. fr), which offered the possibility to evaluate prognostic …

In this review, the evidence for a role of fibroblast growth factor receptor (FGFR) mediated
signalling in carcinogenesis are considered and relevant underlying mechanisms …

The fibroblast growth factor receptors (FGFRs) regulate important biological processes
including cell proliferation and differentiation during development and tissue repair. Over the …