A travel guide to Cytoscape plugins
Cytoscape is open-source software for integration, visualization and analysis of biological
networks. It can be extended through Cytoscape plugins, enabling a broad community of …
networks. It can be extended through Cytoscape plugins, enabling a broad community of …
The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease
Prions are self-templating protein conformers that are naturally transmitted between
individuals and promote phenotypic change. In yeast, prion-encoded phenotypes can be …
individuals and promote phenotypic change. In yeast, prion-encoded phenotypes can be …
The BioMart community portal: an innovative alternative to large, centralized data repositories
Abstract The BioMart Community Portal (www. biomart. org) is a community-driven effort to
provide a unified interface to biomedical databases that are distributed worldwide. The …
provide a unified interface to biomedical databases that are distributed worldwide. The …
KOBAS 2.0: a web server for annotation and identification of enriched pathways and diseases
High-throughput experimental technologies often identify dozens to hundreds of genes
related to, or changed in, a biological or pathological process. From these genes one wants …
related to, or changed in, a biological or pathological process. From these genes one wants …
COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer
SA Forbes, N Bindal, S Bamford, C Cole… - Nucleic acids …, 2010 - academic.oup.com
Abstract COSMIC (http://www. sanger. ac. uk/cosmic) curates comprehensive information on
somatic mutations in human cancer. Release v48 (July 2010) describes over 136 000 …
somatic mutations in human cancer. Release v48 (July 2010) describes over 136 000 …
Characterizing the genetic basis of transcriptome diversity through RNA-sequencing of 922 individuals
Understanding the consequences of regulatory variation in the human genome remains a
major challenge, with important implications for understanding gene regulation and …
major challenge, with important implications for understanding gene regulation and …
[HTML][HTML] International network of cancer genome projects
International Cancer Genome Consortium - Nature, 2010 - ncbi.nlm.nih.gov
Abstract The International Cancer Genome Consortium (ICGC) was launched to coordinate
large-scale cancer genome studies in tumors from 50 different cancer types and/or subtypes …
large-scale cancer genome studies in tumors from 50 different cancer types and/or subtypes …
International Cancer Genome Consortium Data Portal—a one-stop shop for cancer genomics data
Abstract The International Cancer Genome Consortium (ICGC) is a collaborative effort to
characterize genomic abnormalities in 50 different cancer types. To make this data …
characterize genomic abnormalities in 50 different cancer types. To make this data …
[HTML][HTML] A rapid, extensive, and transient transcriptional response to estrogen signaling in breast cancer cells
We report the immediate effects of estrogen signaling on the transcriptome of breast cancer
cells using global run-on and sequencing (GRO-seq). The data were analyzed using a new …
cells using global run-on and sequencing (GRO-seq). The data were analyzed using a new …
The human gene damage index as a gene-level approach to prioritizing exome variants
The protein-coding exome of a patient with a monogenic disease contains about 20,000
variants, only one or two of which are disease causing. We found that 58% of rare variants in …
variants, only one or two of which are disease causing. We found that 58% of rare variants in …