The origin and specification of cortical interneurons

CP Wonders, SA Anderson - Nature Reviews Neuroscience, 2006 - nature.com
GABA-containing interneurons are crucial to both the development and function of the
cerebral cortex. Unlike cortical projection neurons, which have a relatively conserved set of …

Orphan nuclear receptors: from gene to function

V Giguère - Endocrine reviews, 1999 - academic.oup.com
II. Nuclear Receptors: General Concepts A. Anatomy of nuclear receptors B. Mechanisms of
action III. Orphan Nuclear Receptors A. Definition

Natural variation in a neuropeptide Y receptor homolog modifies social behavior and food response in C. elegans

M De Bono, CI Bargmann - Cell, 1998 - cell.com
Natural isolates of C. elegans exhibit either solitary or social feeding behavior. Solitary
foragers move slowly on a bacterial lawn and disperse across it, while social foragers move …

Neurobiological basis of psychopathy

RJR Blair - The British Journal of Psychiatry, 2003 - cambridge.org
BLAIR that there is no generalised frontal cortical dysfunction in individuals with
psychopathy there is one region of the frontal cortex that could be impaired, ie the …

Histone H3. 3 mutations drive pediatric glioblastoma through upregulation of MYCN

L Bjerke, A Mackay, M Nandhabalan, A Burford, A Jury… - Cancer discovery, 2013 - AACR
Children and young adults with glioblastoma (GBM) have a median survival rate of only 12
to 15 months, and these GBMs are clinically and biologically distinct from histologically …

Nuclear receptors — a perspective from Drosophila

K King-Jones, CS Thummel - Nature Reviews Genetics, 2005 - nature.com
Nuclear receptors are ancient ligand-regulated transcription factors that control key
metabolic and developmental pathways. The fruitfly Drosophila melanogaster has only 18 …

MicroRNA let-7b regulates neural stem cell proliferation and differentiation by targeting nuclear receptor TLX signaling

C Zhao, GQ Sun, S Li, MF Lang… - Proceedings of the …, 2010 - National Acad Sciences
Neural stem cell self-renewal and differentiation is orchestrated by precise control of gene
expression involving nuclear receptor TLX. Let-7b, a member of the let-7 microRNA family, is …

A role for adult TLX-positive neural stem cells in learning and behaviour

CL Zhang, Y Zou, W He, FH Gage, RM Evans - Nature, 2008 - nature.com
Neurogenesis persists in the adult brain and can be regulated by a plethora of external
stimuli, such as learning, memory, exercise, environment and stress. Although newly …

miR-137 forms a regulatory loop with nuclear receptor TLX and LSD1 in neural stem cells

GQ Sun, P Ye, K Murai, MF Lang, S Li, H Zhang… - Nature …, 2011 - nature.com
Abstract miR-137 is a brain-enriched microRNA. Its role in neural development remains
unknown. Here we show that miR-137 has an essential role in controlling embryonic neural …

Neurogenetics of aggressive behavior: studies in rodents

A Takahashi, KA Miczek - Neuroscience of aggression, 2014 - Springer
Aggressive behavior is observed in many animal species, such as insects, fish, lizards,
frogs, and most mammals including humans. This wide range of conservation underscores …