Structural framework for the understanding spectroscopic and functional signatures of the cyanobacterial Orange Carotenoid Protein families

NN Sluchanko, EG Maksimov, YB Slonimskiy… - International Journal of …, 2024 - Elsevier
Abstract The Orange Carotenoid Protein (OCP) is a unique photoreceptor crucial for
cyanobacterial photoprotection. Best studied Synechocystis sp. PCC 6803 OCP belongs to …

Applications of ancestral sequence reconstruction for understanding the evolution of plant specialized metabolism

TJ Barkman - Philosophical Transactions B, 2024 - royalsocietypublishing.org
Studies of enzymes in modern-day plants have documented the diversity of metabolic
activities retained by species today but only provide limited insight into how those properties …

Lipid composition and properties affect protein-mediated carotenoid uptake efficiency from membranes

K Likkei, M Moldenhauer, NN Tavraz… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Carotenoids are pigments of diverse functions ranging from coloration over light-harvesting
to photoprotection. Yet, the number of carotenoid-binding proteins, which mobilize these …

A functional map of the human intrinsically disordered proteome

I Pritišanac, TR Alderson, Đ Kolarić, T Zarin, S Xie… - bioRxiv, 2024 - biorxiv.org
Intrinsically disordered regions (IDRs) represent at least one-third of the human proteome
and defy the established structure-function paradigm. Because IDRs often have limited …

Evolution of affinity between p53 transactivation domain and MDM2 across the animal kingdom demonstrates high plasticity of motif‐mediated interactions

F Mihalič, E Åberg, P Farkhondehkish, N Theys… - Protein …, 2023 - Wiley Online Library
The interaction between the transcription factor p53 and the ubiquitin ligase MDM2 results in
the degradation of p53 and is well‐studied in cancer biology and drug development …

[HTML][HTML] Elements of the C-terminal tail of a C-terminal domain homolog of the Orange Carotenoid Protein determining xanthophyll uptake from liposomes

K Likkei, M Moldenhauer, NN Tavraz… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Carotenoids perform multifaceted roles in life ranging from coloration over light harvesting to
photoprotection. The Orange Carotenoid Protein (OCP), a light-driven photoswitch involved …

Evolution of affinity between p53 and MDM2 across the animal kingdom demonstrates high plasticity of motif-mediated interactions

F Mihalic, E Åberg, P Farkhondehkish, N Theys… - bioRxiv, 2023 - biorxiv.org
The interaction between the transcription factor p53 and the ubiquitin ligase MDM2 results in
degradation of p53 and is well studied in cancer biology and drug development. Available …

Ion-Powered Rotary Motors: Where Did They Come from and Where They Are Going?

V Nandel, J Scadden, MAB Baker - International Journal of Molecular …, 2023 - mdpi.com
Molecular motors are found in many living organisms. One such molecular machine, the ion-
powered rotary motor (IRM), requires the movement of ions across a membrane against a …

Evolution of molecular innovations in cyanobacterial light-perceiving systems

N Steube - 2023 - archiv.ub.uni-marburg.de
Novel functional features are prominent throughout evolution, yet paradoxical: how does
evolution create something innovative when all it can work with is variation of established …

[PDF][PDF] BBA-Bioenergetics

K Likkei, M Moldenhauer, NN Tavraz, NA Egorkin - depositonce.tu-berlin.de
Carotenoids perform multifaceted roles in life ranging from coloration over light harvesting to
photoprotection. The Orange Carotenoid Protein (OCP), a light-driven photoswitch involved …