A decennary update on diverse heterocycles and their intermediates as privileged scaffolds for cathepsin B inhibition
The identification of x-ray crystal structure of cathepsin B (CTSB) in the early 90's enabled
researchers to embark on a journey to understand and demystify its multiple catalytic …
researchers to embark on a journey to understand and demystify its multiple catalytic …
α-Halogenoacetamides: versatile and efficient tools for the synthesis of complex aza-heterocycles
A El Bouakher, A Martel, S Comesse - Organic & Biomolecular …, 2019 - pubs.rsc.org
This review provides an overview of the applications of α-halogenoacetamides in domino
and cycloaddition reactions. α-Halogenoacetamides are versatile building blocks that can …
and cycloaddition reactions. α-Halogenoacetamides are versatile building blocks that can …
New potent ciprofloxacin-uracil conjugates as DNA gyrase and topoisomerase IV inhibitors against methicillin-resistant Staphylococcus aureus
A series of ciprofloxacin-uracil conjugates 5a-t were synthesized and identified by 1 H NMR,
13 C NMR, mass spectroscopy and elemental analyses. The antibacterial results revealed …
13 C NMR, mass spectroscopy and elemental analyses. The antibacterial results revealed …
Synthesis and anticancer evaluation of some novel 5‐amino [1, 2, 4] triazole derivatives
AY Hassan, MT Sarg, AH Bayoumi… - Journal of Heterocyclic …, 2018 - Wiley Online Library
Novel [1, 2, 4] triazole derivatives were synthesized via various synthetic pathways. Among
which were different substituted [1, 2, 4] triazole analogues that were synthesized, in …
which were different substituted [1, 2, 4] triazole analogues that were synthesized, in …
Characteristics of multidentate Schiff base ligand and its complexes using cyclic voltammetry, fluorescence, antimicrobial behavior and DFT-calculations
AM Fathi, HS Mandour, E HassaneAnouar - Journal of Molecular Structure, 2021 - Elsevier
The electrochemical behavior of a series of the metal complexes [Fe (III), Ni (II), Ru (III), Pd
(II) and Hf (IV)] derived from the Schiff base ligand (E)-5-((phenyl (-pyridin-2-yl) methylene) …
(II) and Hf (IV)] derived from the Schiff base ligand (E)-5-((phenyl (-pyridin-2-yl) methylene) …
Synthesis, characterization and molecular modeling of some transition metal complexes of Schiff base derived from 5-aminouracil and 2-benzoyl pyridine
YK Abdel-Monem, SA Abouel-Enein, M Safa - Journal of Molecular …, 2018 - Elsevier
Abstract Multidentate Schiff base (H 2 L) ligand results from condensation of 5-aminouracil
and 2-benzoyl pyridine and its metal chloride (Mn (II), Co (II), Ni (II), Cu (II), Zn (II), Pd (II), Fe …
and 2-benzoyl pyridine and its metal chloride (Mn (II), Co (II), Ni (II), Cu (II), Zn (II), Pd (II), Fe …
Multi‐Component Reaction of 6‐Aminouracils, Aldehydes and Secondary Amines: Conversion of the Products into Pyrimido[4,5‐d]pyrimidines through C‐H …
PJ Borpatra, GK Rastogi, MBS Saikia, ML Deb… - …, 2019 - Wiley Online Library
Reaction of 6‐aminouracils with aldehydes and secondary amines catalyzed by acetic acid
is reported here. This is in fact a domino aza‐Michael reaction. 6‐Aminouracil reacts first …
is reported here. This is in fact a domino aza‐Michael reaction. 6‐Aminouracil reacts first …
Catalyst-free, efficient, and green procedure for the synthesis of 5-heterocyclic substituted 6-aminouracils
A Jamaledini, MR Mohammadizadeh… - Monatshefte für Chemie …, 2018 - Springer
In this paper, the results of our studies on the catalyst-free synthesis of some new 6-
aminouracils bearing naphthoquinone, benzo [a] phenazine, benzo [f] pyrido [2, 3-b] …
aminouracils bearing naphthoquinone, benzo [a] phenazine, benzo [f] pyrido [2, 3-b] …
Synthesis of Quinoxalines
VA Mamedov, VA Mamedov - Quinoxalines: Synthesis, Reactions …, 2016 - Springer
The synthesis of quinoxalines has been intensively studied in the past, especially because
of the diverse biological activities ascribed to many representatives of this class of …
of the diverse biological activities ascribed to many representatives of this class of …
[PDF][PDF] СИНТЕЗ ЗАМІЩЕНИХ ПІРОЛО [2, 3-d] ПІРИМІДИНІВ ТА ПІРИДО [2, 3-d] ПІРИМІДИНІВ В ОДНОРЕАКТОРНІЙ КОНДЕНСАЦІЇ 2-ТІО-6-АМІНОУРАЦИЛУ …
HМ Колос, НВ Чечина - … університету імені ВН …, 2019 - chembull.univer.kharkov.ua
Розроблено доступні і ефективні методи синтезу заміщених піроло [2, 3-d] піримідинів і
5, 8-дигідропіридо [2, 3-d] піримідинів засновані на трикомпонентній конденсації 6 …
5, 8-дигідропіридо [2, 3-d] піримідинів засновані на трикомпонентній конденсації 6 …