Epicardial adipose tissue in contemporary cardiology
G Iacobellis - Nature reviews cardiology, 2022 - nature.com
Interest in epicardial adipose tissue (EAT) is growing rapidly, and research in this area
appeals to a broad, multidisciplinary audience. EAT is unique in its anatomy and …
appeals to a broad, multidisciplinary audience. EAT is unique in its anatomy and …
Emerging therapeutic approaches for the treatment of NAFLD and type 2 diabetes mellitus
D Ferguson, BN Finck - Nature Reviews Endocrinology, 2021 - nature.com
Non-alcoholic fatty liver disease (NAFLD) has emerged as the most prevalent liver disease
in the world, yet there are still no approved pharmacological therapies to prevent or treat this …
in the world, yet there are still no approved pharmacological therapies to prevent or treat this …
Effect of tirzepatide versus insulin degludec on liver fat content and abdominal adipose tissue in people with type 2 diabetes (SURPASS-3 MRI): a substudy of the …
A Gastaldelli, K Cusi, LF Landó, R Bray… - The lancet Diabetes & …, 2022 - thelancet.com
Background Tirzepatide is a novel dual glucose-dependent insulinotropic polypeptide (GIP)
and glucagon-like peptide-1 receptor agonist under development for the treatment of type 2 …
and glucagon-like peptide-1 receptor agonist under development for the treatment of type 2 …
Obesity and nonalcoholic fatty liver disease: From pathophysiology to therapeutics
The obesity epidemic is closely associated with the rising prevalence and severity of
nonalcoholic fatty liver disease (NAFLD): obesity has been linked not only with simple …
nonalcoholic fatty liver disease (NAFLD): obesity has been linked not only with simple …
[HTML][HTML] Nonalcoholic fatty liver disease (NAFLD) from pathogenesis to treatment concepts in humans
K Pafili, M Roden - Molecular Metabolism, 2021 - Elsevier
Background Nonalcoholic fatty liver disease (NAFLD) comprises hepatic alterations with
increased lipid accumulation (steatosis) without or with inflammation (nonalcoholic …
increased lipid accumulation (steatosis) without or with inflammation (nonalcoholic …
Efficacy of peroxisome proliferator-activated receptor agonists, glucagon-like peptide-1 receptor agonists, or sodium-glucose cotransporter-2 inhibitors for treatment of …
A Mantovani, CD Byrne, G Targher - The lancet Gastroenterology & …, 2022 - thelancet.com
There are no licensed treatments for non-alcoholic fatty liver disease (NAFLD), but three
different classes of antihyperglycaemic drugs—peroxisome proliferator-activated receptor …
different classes of antihyperglycaemic drugs—peroxisome proliferator-activated receptor …
Glucagon-like peptide-1 receptor agonists for treatment of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis: an updated meta-analysis of randomized …
A Mantovani, G Petracca, G Beatrice, A Csermely… - Metabolites, 2021 - mdpi.com
To assess the efficacy of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) for
treatment of nonalcoholic fatty liver disease (NAFLD) or steatohepatitis (NASH), we …
treatment of nonalcoholic fatty liver disease (NAFLD) or steatohepatitis (NASH), we …
GLP-1 receptor agonists in non-alcoholic fatty liver disease: current evidence and future perspectives
R Nevola, R Epifani, S Imbriani, G Tortorella… - International Journal of …, 2023 - mdpi.com
To date, non-alcoholic fatty liver disease (NAFLD) is the most frequent liver disease,
affecting up to 70% of patients with diabetes. Currently, there are no specific drugs available …
affecting up to 70% of patients with diabetes. Currently, there are no specific drugs available …
Epicardial adipose tissue may mediate deleterious effects of obesity and inflammation on the myocardium
M Packer - Journal of the American College of Cardiology, 2018 - jacc.org
Epicardial adipose tissue has unique properties that distinguish it from other depots of
visceral fat. Rather than having distinct boundaries, the epicardium shares an unobstructed …
visceral fat. Rather than having distinct boundaries, the epicardium shares an unobstructed …
Metabolic implications of pancreatic fat accumulation
Fat accumulation outside subcutaneous adipose tissue often has unfavourable effects on
systemic metabolism. In addition to non-alcoholic fatty liver disease, which has received …
systemic metabolism. In addition to non-alcoholic fatty liver disease, which has received …