Sustained tissue hypoxia is associated with many pathophysiological conditions, including
chronic inflammation, chronic wounds, slow-healing fractures, microvascular complications …

Multiple studies implicate iron accumulation in the substantia nigra in the degeneration of
dopaminergic neurons in Parkinson's disease. Indeed, slowing of iron accumulation in cells …

Recent findings underscore that some natural compounds are responsible for specific
biochemical effects, ie, the activation of redox‐sensitive intracellular pathways and …

Chronic obstructive pulmonary disease (COPD) is a progressive lung disease characterized
by severe respiratory symptoms. COPD shows several hallmarks of aging, and an increased …

Transglutaminase 2 (TG2) is a multifunctional enzyme and two isoforms, TG2-L and TG2-S,
exerting opposite effects in the regulation of cell death and survival, have been revealed in …

The present study aimed to evaluate the efficacy of an intra-arterially infused carbon dioxide
(CO2)-saturated solution in sensitizing the anticancer effect of cisplatin in a rabbit VX2 liver …

Abstract This chapter entitled “Cell Cycle, DNA Damage Repair Systems, and Impact of
Redox Regulation in Cancer” introduces the cell cycle components in normal cells and …

Introduction CO 2 pneumoperitoneum can influence the biological behavior of
neuroblastoma (NB). Angiogenesis and genetic features are responsible for malignant …

Purpose The proto-oncogene MYCN is considered a transcription factor involved in the
regulation of neuroblastoma (NB) cell biology. Since minimally invasive-surgery represents …

Purpose To evaluate the efficacy of intraarterial infusion of CO 2-saturated solution in rabbit
VX2 thigh tumors. Materials and Methods Fourteen Japanese white rabbits had VX2 tumors …