Amorphous solid dispersions (ASDs) are popular for enhancing the solubility and
bioavailability of poorly water-soluble drugs. Various approaches have been employed to …

Pharmaceutical cocrystals are multicomponent systems in which at least one component is
an active pharmaceutical ingredient and the others are pharmaceutically acceptable …

Originally discovered almost a century ago, cocrystals continue to gain interest in the
modern day due to their ability to modify the physical properties of solid-state materials …

Poor water solubility of many drugs has emerged as one of the major challenges in the
pharmaceutical world. Polymer-based amorphous solid dispersions have been considered …

The development of oral dosage forms for poorly water-soluble active pharmaceutical
ingredients (APIs) is a persistent challenge. A range of methods has been explored to …

Amorphous products and particularly amorphous solid dispersions are currently one of the
most exciting areas in the pharmaceutical field. This approach presents huge potential and …

Purpose The fabrication of ready-to-use immediate release tablets via 3D printing provides a
powerful tool to on-demand individualization of dosage form. This work aims to adapt a …

Pharmaceutical cocrystals are multicomponent systems composed of two or more molecules
and held together by H-bonding. Currently, cocrystals provide exciting opportunities in the …

Over the last few decades, hot melt extrusion (HME) has emerged as a successful
technology for a broad spectrum of applications in the pharmaceutical industry. As indicated …

The objective of this study was to develop a new approach for fabrication of zero order
release of active pharmaceutical ingredients (APIs) using hot-melt extrusion (HME) and 3D …