mRNA Cancer vaccines: construction and boosting strategies
In late 2020, the US Food and Drug Administration (FDA) approved a lipid-based mRNA
vaccine for the prevention of COVID-19, which has pushed this field to be more closely …
vaccine for the prevention of COVID-19, which has pushed this field to be more closely …
Nanovaccine: An emerging strategy
A Das, N Ali - Expert review of vaccines, 2021 - Taylor & Francis
Introduction Vaccination is so far the most effective way of eradicating infections. Rapidly
emerging drug resistance against infectious diseases and chemotherapy-related toxicities in …
emerging drug resistance against infectious diseases and chemotherapy-related toxicities in …
Lipid nanoparticle-based mRNA vaccines in cancers: Current advances and future prospects
T Huang, L Peng, Y Han, D Wang, X He… - Frontiers in …, 2022 - frontiersin.org
Messenger RNA (mRNA) vaccines constitute an emerging therapeutic method with the
advantages of high safety and efficiency as well as easy synthesis; thus, they have been …
advantages of high safety and efficiency as well as easy synthesis; thus, they have been …
Recent advances in cancer vaccines: challenges, achievements, and futuristic prospects
Cancer is a chronic disease, and it can be lethal due to limited therapeutic options. The
conventional treatment options for cancer have numerous challenges, such as a low blood …
conventional treatment options for cancer have numerous challenges, such as a low blood …
Virus-like particle-templated silica-adjuvanted nanovaccines with enhanced humoral and cellular immunity
M Li, Z Liang, C Chen, G Yu, Z Yao, Y Guo, L Zhang… - ACS …, 2022 - ACS Publications
Virus-like particles (VLPs) are self-assembled viral proteins that represent a superior form of
antigens in vaccine formulations. To enhance immunogenicity, adjuvants, especially the …
antigens in vaccine formulations. To enhance immunogenicity, adjuvants, especially the …
Mannose in vaccine delivery
Adjuvants and vaccine delivery systems are used widely to improve the efficacy of vaccines.
Their primary roles are to protect antigen from degradation and allow its delivery and uptake …
Their primary roles are to protect antigen from degradation and allow its delivery and uptake …
Hollow aluminum hydroxide modified silica nanoadjuvants with amplified immunotherapy effects through immunogenic cell death induction and antigen release
In spite of the widespread application of vaccine adjuvants in various preventive vaccines at
present, the existing adjuvants are still hindered by weak cellular immunity responses in …
present, the existing adjuvants are still hindered by weak cellular immunity responses in …
Understanding structure–function relationships of nanoadjuvants for enhanced cancer vaccine efficacy
J Tan, B Ding, B Teng, P Ma… - Advanced Functional …, 2022 - Wiley Online Library
Adjuvant, as an important part of vaccines, can observably enhance the magnitude, breadth
and durability of immune responses. Nanoadjuvants, as novel vaccine adjuvants, have …
and durability of immune responses. Nanoadjuvants, as novel vaccine adjuvants, have …
Nanoparticle-based adjuvants and delivery systems for modern vaccines
Ever since the development of the first vaccine, vaccination has had the great impact on
global health, leading to the decrease in the burden of numerous infectious diseases …
global health, leading to the decrease in the burden of numerous infectious diseases …
[HTML][HTML] Nanocarrier vaccine therapeutics for global infectious and chronic diseases
Immunization has the potential to become a viable weapon for the upcoming pandemic and
save millions of lives, while also dramatically lowering the high mortality rate brought on by a …
save millions of lives, while also dramatically lowering the high mortality rate brought on by a …