The IL-4, IL-13 and IL-31 pathways in atopic dermatitis

C Dubin, E Del Duca… - Expert review of clinical …, 2021 - Taylor & Francis
Introduction: Atopic dermatitis (AD) is the most common inflammatory skin disease. It has a
complex pathophysiology, with a combination of immune dysregulation and intrinsic barrier …

The skin microbiome of vertebrates

AA Ross, A Rodrigues Hoffmann, JD Neufeld - Microbiome, 2019 - Springer
The skin constitutes the primary physical barrier between vertebrates and their external
environment. Characterization of skin microorganisms is essential for understanding how a …

Single-cell transcriptome analysis of human skin identifies novel fibroblast subpopulation and enrichment of immune subsets in atopic dermatitis

H He, H Suryawanshi, P Morozov… - Journal of Allergy and …, 2020 - Elsevier
Background Atopic dermatitis (AD) is a prevalent inflammatory skin disease with a complex
pathogenesis involving immune cell and epidermal abnormalities. Despite whole tissue …

[PDF][PDF] Skin Barrier Damage and Itch: Review of Mechanisms, Topical Management and Future Directions.

G Yosipovitch, L Misery, E Proksch… - Acta dermato …, 2019 - pdfs.semanticscholar.org
The sensation of itch can arise from the activation of epidermal nerve fibres that either
belong to a specialised class of itch-provoking neurons (“pruriceptors”) or that are …

[图书][B] Атопический дерматит у детей

ИИ Балаболкин, ВА Булгакова, ТИ Елисеева - 2018 - elibrary.ru
В издании обобщены исследования авторов и литературные данные по проблеме
атопического дерматита у детей. Представлены эпидемиология, этиология, патогенез …

Mild atopic dermatitis lacks systemic inflammation and shows reduced nonlesional skin abnormalities

H He, E Del Duca, A Diaz, HJ Kim… - Journal of Allergy and …, 2021 - Elsevier
Background Molecular studies in atopic dermatitis (AD) are largely restricted to patients with
moderate-to-severe disease. Objective Our aim was to evaluate skin and blood …

Overcome the barriers of the skin: exosome therapy

GH Yang, YB Lee, D Kang, E Choi, Y Nam, KH Lee… - Biomaterials …, 2021 - Springer
Exosomes are nano-sized cargos with a lipid bilayer structure carrying diverse biomolecules
including lipids, proteins, and nucleic acids. These small vesicles are secreted by most types …

Identification of novel immune and barrier genes in atopic dermatitis by means of laser capture microdissection

H Esaki, DA Ewald, B Ungar, M Rozenblit… - Journal of Allergy and …, 2015 - Elsevier
Background The molecular signature of atopic dermatitis (AD) lesions is associated with TH
2 and TH 22 activation and epidermal alterations. However, the epidermal and dermal AD …

Current insights into immunology and novel therapeutics of atopic dermatitis

HA Kader, M Azeem, SA Jwayed, A Al-Shehhi… - Cells, 2021 - mdpi.com
Atopic dermatitis (AD) is one of the most prevalent inflammatory disease among non-fatal
skin diseases, affecting up to one fifth of the population in developed countries. AD is …

Tape-strip proteomic profiling of atopic dermatitis on dupilumab identifies minimally invasive biomarkers

H He, CM Olesen, AB Pavel, ML Clausen… - Frontiers in …, 2020 - frontiersin.org
Tape-stripping is a minimally invasive approach for skin sampling that captures the
cutaneous immune/barrier abnormalities in atopic dermatitis (AD). However, tape-strips …