Abstract Interleukin-6 (IL-6) is a pleiotropic pro-inflammatory cytokine. Its deregulation is
associated with chronic inflammation, and multifactorial auto-immune disorders. It mediates …

Isoquinoline alkaloids, an important class of N‐based heterocyclic compounds, have
attracted considerable attention from researchers worldwide since the early 19th century …

The present study examined the biological potential and phytochemicals of Sophora mollis,
Mucuna pruriens, and Indigofera atropurpurea methanolic leaf extracts. In vitro anti …

Gastric cancer is among the major causes of death from neoplasia leading causes of death
worldwide, with high incidence rates and problems related to its treatment. Here, we outline …

The severe anticancer situation as well as the emergence of multidrug-resistant (MDR)
cancer cells has created an urgent need for the development of novel anticancer drugs with …

Ethnopharmacological relevance Neurodegenerative diseases are neuronal diseases that
affect the brain components by degenerating the structure and function of the central or …

Infectious diseases remain a significant threat to human health, contributing to more than 17
million deaths, annually. With the worsening trends of drug resistance, there is a need for …

A tetrahydroisoquinoline identified in Mucuna pruriens ((1 R, 3 S)-6, 7-dihydroxy-1-methyl-1,
2, 3, 4-tetrahydroisoquinoline-1, 3-dicarboxylic acid, compound 4) was synthesized and …

Colorectal cancer (CRC) is the third most common malignant tumor in the world, and it is
prone to recurrence and metastasis during treatment. Aerobic glycolysis is one of the main …

Abstract Globally, 15–24% couples are unable to conceive naturally and 50% of cases of
this problem are due to infertility in males. Of this, about 50% of male infertility problems are …