Pyrazole-based analogs as potential antibacterial agents against methicillin-resistance staphylococcus aureus (MRSA) and its SAR elucidation
Methicillin-resistant Staphylococcus aureus (MRSA) is becoming lethal to humanity due to
easy transmission and difficult-to-treat skin and flimsy diseases. The most threatening aspect …
easy transmission and difficult-to-treat skin and flimsy diseases. The most threatening aspect …
Oxidative stress, eryptosis and anemia: a pivotal mechanistic nexus in systemic diseases
R Bissinger, AAM Bhuyan, SM Qadri… - The FEBS …, 2019 - Wiley Online Library
The average lifespan of circulating erythrocytes usually exceeds hundred days. Prior to that,
however, erythrocytes may be exposed to oxidative stress in the circulation which could …
however, erythrocytes may be exposed to oxidative stress in the circulation which could …
Heterogeneous graphitic carbon nitrides in visible-light-initiated organic transformations
In recent years, g-C3N4 photocatalyst-mediated organic reactions have represented an
important mode of chemical transformations and are expected to become a crucial field at …
important mode of chemical transformations and are expected to become a crucial field at …
Benzimidazole analogues as efficient arsenals in war against methicillin-resistance staphylococcus aureus (MRSA) and its SAR studies
Small molecule based inhibitors development is a growing field in medicinal chemistry. In
recent years, different heterocyclic derivatives have been designed to counter the infections …
recent years, different heterocyclic derivatives have been designed to counter the infections …
Pathophysiology of red blood cell dysfunction in diabetes and its complications
A Williams, R Bissinger, H Shamaa, S Patel, L Bourne… - Pathophysiology, 2023 - mdpi.com
Diabetes Mellitus (DM) is a complex metabolic disorder associated with multiple
microvascular complications leading to nephropathy, retinopathy, and neuropathy. Mounting …
microvascular complications leading to nephropathy, retinopathy, and neuropathy. Mounting …
Fluorinated azoles as effective weapons in fight against methicillin-resistance staphylococcus aureus (MRSA) and its SAR studies
The rapid spread of Methicillin-resistant Staphylococcus aureus (MRSA) and its difficult-to-
treat skin and filmsy diseases are making MRSA a threat to human life. The most dangerous …
treat skin and filmsy diseases are making MRSA a threat to human life. The most dangerous …
Apoptosis and eryptosis: similarities and differences
A Tkachenko - Apoptosis, 2024 - Springer
Eryptosis is a regulated cell death (RCD) of mature erythrocytes initially described as a
counterpart of apoptosis for enucleated cells. However, over the recent years, a growing …
counterpart of apoptosis for enucleated cells. However, over the recent years, a growing …
Structure-activity relationship studies of thiazole agents with potential anti methicillin-resistance Staphylococcus aureus (MRSA) activity
Due to the increasing resistance of methicillin-resistant Staphylococcus aureus (MRSA) to
conventional antibiotics, further efforts are needed to develop new antimicrobial agents …
conventional antibiotics, further efforts are needed to develop new antimicrobial agents …
Carbonyl stress in red blood cells and hemoglobin
OV Kosmachevskaya, NN Novikova, AF Topunov - Antioxidants, 2021 - mdpi.com
The paper overviews the peculiarities of carbonyl stress in nucleus-free mammal red blood
cells (RBCs). Some functional features of RBCs make them exceptionally susceptible to …
cells (RBCs). Some functional features of RBCs make them exceptionally susceptible to …
[HTML][HTML] Inhibition of phosphodiesterase 4 by FCPR16 protects SH-SY5Y cells against MPP+-induced decline of mitochondrial membrane potential and oxidative …
J Zhong, H Yu, C Huang, Q Zhong, Y Chen, J Xie… - Redox biology, 2018 - Elsevier
Abstract Phosphodiesterase 4 (PDE4) is a promising target for the treatment of Parkinson's
disease (PD). However, the underlying mechanism has not yet been well elucidated …
disease (PD). However, the underlying mechanism has not yet been well elucidated …