Host-tumor relationships involve several factors that can enhance or suppress neoplastic
growth. This second part of a review of basal cell carcinoma biology examines the role that …

The importance of wool in the textile industry has inspired extensive research into its
structure since the 1960s. Over the past several years, however, the hair follicle has …

This paper investigates the ceramide composition of the psoriatic scale compared with that
of normal human SC. A method was optimalized, based on TLC separation followed by …

Hedgehog (HH) signaling proteins mediate inductive events during animal development1–
11. Mutation of the only known HH receptor gene, Patched (PTC), has recently been …

In the present study, we demonstrate that human stratum corneum contains covalently
bound lipids accounting for 1.4% of the dry weight of the tissue. The major component …

Human keratinocytes were grown on a dermal equivalent (or lattice) at the liquid-air
interface in an attempt to reconstitute a functional epidermis in vitro. Although the …

Skin regeneration is an important area of research in the field of tissue-engineering,
especially for cases involving loss of massive areas of skin, where current treatments are not …

Co-expression of several members of the matrix metalloproteinase (MMP) family is a
characteristic of human carcinomas. To investigate the role of the recently cloned …

The in vitro tests in current research employ simple culture methods that fail to mimic the real
human tissue. In this study, we report drug testing with a 'pumpless skin-on-a-chip'that …

Stratified epithelium displays an equilibrium between proliferation and cell cycle arrest, a
balance that is disrupted in basal cell carcinoma (BCC). Sonic hedgehog (Shh) pathway …