[HTML][HTML] Harnessing tissue-derived extracellular vesicles for osteoarthritis theranostics

B Yin, J Ni, CE Witherel, M Yang, JA Burdick, C Wen… - Theranostics, 2022 - ncbi.nlm.nih.gov
Osteoarthritis (OA) is a prevalent chronic whole-joint disease characterized by low-grade
systemic inflammation, degeneration of joint-related tissues such as articular cartilage, and …

Global research trends in stem cells for osteoarthritis: a bibliometric and visualized study

D Xing, Y Zhao, S Dong, J Lin - International journal of …, 2018 - Wiley Online Library
Aim There have been increased interests in the use of stems cells in the research of
osteoarthritis (OA). The present study aimed to investigate the global status and trends in …

Intra-articular injection of mesenchymal stem cells for the treatment of osteoarthritis of the knee: a 2-year follow-up study

CH Jo, JW Chai, EC Jeong, S Oh… - … American journal of …, 2017 - journals.sagepub.com
Background: The intra-articular injection of mesenchymal stem cells (MSCs) into the knee
has shown a potential for the treatment of generalized cartilage loss in osteoarthritis (OA) …

Inflammation-modulating hydrogels for osteoarthritis cartilage tissue engineering

RH Koh, Y Jin, J Kim, NS Hwang - Cells, 2020 - mdpi.com
Osteoarthritis (OA) is the most common form of the joint disease associated with age,
obesity, and traumatic injury. It is a disabling degenerative disease that affects synovial …

Cell-laden injectable microgels: Current status and future prospects for cartilage regeneration

TPT Nguyen, F Li, S Shrestha, RS Tuan, H Thissen… - Biomaterials, 2021 - Elsevier
Injectable hydrogels have been employed extensively as versatile materials for cartilage
regeneration due to their excellent biocompatibility, tunable structure, and ability to …

The effect of intra‐articular injection of autologous bone marrow stem cells on pain and knee function in patients with osteoarthritis

D Garay‐Mendoza, L Villarreal‐Martínez… - … journal of rheumatic …, 2018 - Wiley Online Library
Aim Management of osteoarthritis (OA) is basically symptomatic. Recently, stem cells (SC)
have been used in the search for an optimum treatment. We decided to conduct a controlled …

Calvarial versus long bone: implications for tailoring skeletal tissue engineering

D Wang, JR Gilbert, X Zhang, B Zhao… - … Engineering Part B …, 2020 - liebertpub.com
Tissue-engineered graft substitutes have shown great potential to treat large bone defects.
While we usually assume that therapeutic approaches developed for appendicular bone …

Allogeneic mesenchymal stromal cells for cartilage regeneration: A review of in vitro evaluation, clinical experience, and translational opportunities

ED Aldrich, X Cui, CA Murphy, KS Lim… - Stem cells …, 2021 - academic.oup.com
The paracrine signaling, immunogenic properties and possible applications of
mesenchymal stromal cells (MSCs) for cartilage tissue engineering and regenerative …

A novel technique for accelerated culture of murine mesenchymal stem cells that allows for sustained multipotency

CM Caroti, H Ahn, HF Salazar, G Joseph, SB Sankar… - Scientific reports, 2017 - nature.com
Bone marrow derived mesenchymal stem cells (MSCs) are regularly utilized for translational
therapeutic strategies including cell therapy, tissue engineering, and regenerative medicine …

Intra-articular injection of kartogenin-enhanced bone marrow–derived mesenchymal stem cells in the treatment of knee osteoarthritis in a rat model

WN Zeng, Y Zhang, D Wang, YP Zeng… - … American Journal of …, 2021 - journals.sagepub.com
Background: In this study, we investigated the in vitro and in vivo chondrogenic capacity of
kartogenin (KGN)–enhanced bone marrow–derived mesenchymal stem cells (BMSCs) for …