[HTML][HTML] Molecular targets, therapeutic agents and multitasking nanoparticles to deal with cancer stem cells: A narrative review
There is increasing evidence that malignant tumors are initiated and maintained by a sub-
population of tumor cells that have similar biological properties to normal adult stem cells …
population of tumor cells that have similar biological properties to normal adult stem cells …
[HTML][HTML] Application of aptamer-drug delivery system in the therapy of breast cancer
R Fan, X Tao, X Zhai, Y Zhu, Y Li, Y Chen… - Biomedicine & …, 2023 - Elsevier
Despite significant treatment advances, breast cancer remains the leading cause of cancer
death in women. From the current treatment situation, in addition to developing …
death in women. From the current treatment situation, in addition to developing …
Optimizing cisplatin delivery to triple-negative breast cancer through novel EGFR aptamer-conjugated polymeric nanovectors
L Agnello, S Tortorella, A d'Argenio, C Carbone… - Journal of Experimental …, 2021 - Springer
Background Management of triple-negative breast cancer (TNBC) is still challenging
because of its aggressive clinical behavior and limited targeted treatment options. Cisplatin …
because of its aggressive clinical behavior and limited targeted treatment options. Cisplatin …
Breast cancer: from pathophysiology to novel therapeutic approaches 2.0
A Zannetti - International Journal of Molecular Sciences, 2023 - mdpi.com
Breast cancer (BC) is the most common malignancy in women worldwide. It is a very
heterogeneous disease characterized by different molecular profiles that are clinically …
heterogeneous disease characterized by different molecular profiles that are clinically …
Aptamer-functionalized nanoparticles mediate PD-L1 siRNA delivery for effective gene silencing in triple-negative breast cancer cells
S Camorani, S Tortorella, L Agnello, C Spanu… - Pharmaceutics, 2022 - mdpi.com
Small interfering RNA (siRNA) therapies require effective delivery vehicles capable of
carrying the siRNA cargo into target cells. To achieve tumor-targeting, a drug delivery …
carrying the siRNA cargo into target cells. To achieve tumor-targeting, a drug delivery …
Aptamer targeted therapy potentiates immune checkpoint blockade in triple-negative breast cancer
S Camorani, M Passariello, L Agnello… - Journal of Experimental …, 2020 - Springer
Background Triple-negative breast cancer (TNBC) is a uniquely aggressive cancer with high
rates of relapse due to resistance to chemotherapy. TNBC expresses higher levels of …
rates of relapse due to resistance to chemotherapy. TNBC expresses higher levels of …
Selective photo-assisted eradication of Triple-Negative breast cancer cells through aptamer decoration of doped conjugated polymer nanoparticles
Photodynamic therapy (PDT) may be an excellent alternative in the treatment of breast
cancer, mainly for the most aggressive type with limited targeted therapies such as triple …
cancer, mainly for the most aggressive type with limited targeted therapies such as triple …
Profiling cancer cells by cell-SELEX: use of aptamers for discovery of actionable biomarkers and therapeutic applications thereof
The identification of tumor cell-specific surface markers is a key step towards personalized
cancer medicine, allowing early assessment and accurate diagnosis, and development of …
cancer medicine, allowing early assessment and accurate diagnosis, and development of …
Tissue Inhibitor of Metalloproteinases-1 Overexpression Mediates Chemoresistance in Triple-Negative Breast Cancer Cells
L Agnello, A d'Argenio, A Caliendo, R Nilo, A Zannetti… - Cells, 2023 - mdpi.com
Triple-negative breast cancer (TNBC) is among the most aggressive breast cancer subtypes.
Despite being initially responsive to chemotherapy, patients develop drug-resistant and …
Despite being initially responsive to chemotherapy, patients develop drug-resistant and …
Selection of a novel cell-internalizing RNA aptamer specific for CD22 antigen in B cell acute lymphoblastic leukemia
D Ruiz-Ciancio, LH Lin, S Veeramani… - … Therapy-Nucleic Acids, 2023 - cell.com
Despite improvements in B cell acute lymphoblastic leukemia (B-ALL) treatment, a
significant number of patients experience relapse of the disease, resulting in poor prognosis …
significant number of patients experience relapse of the disease, resulting in poor prognosis …