Sharp wave ripples (SPW‐Rs) represent the most synchronous population pattern in the
mammalian brain. Their excitatory output affects a wide area of the cortex and several …

In the immature brain, GABA (γ-aminobutyric acid) is excitatory, and GABA-releasing
synapses are formed before glutamatergic contacts in a wide range of species and …

Developing networks follow common rules to shift from silent cells to coactive networks that
operate via thousands of synapses. This review deals with some of these rules and in …

The developing brain is talkative but its language is not that of the adult. Most if not all
voltage and transmitter-gated ionic currents follow a developmental sequence and network …

In the mature brain, GABA (γ-aminobutyric acid) functions primarily as an inhibitory
neurotransmitter. But it can also act as a trophic factor during nervous system development …

Estradiol is the most potent and ubiquitous member of a class of steroid hormones called
estrogens. Fetuses and newborns are exposed to estradiol derived from their mother, their …

GABA is the main inhibitory neurotransmitter in the adult brain. Early in development,
however, GABAergic synaptic transmission is excitatory and can exert widespread trophic …

INTRODUCTION During development, brain circuits go through phases of synapse
formation, stabilization, or elimination. γ-aminobutyric acid–mediated (GABAergic) synapse …

The main ionotropic receptors (GABA A, NMDA and AMPA) display a sequential
participation in neuronal excitation in the neonatal hippocampus. GABA, the principal …

GABA is the principal inhibitory neurotransmitter in the mature brain, but during early
postnatal development the elevated [Cl−] i in immature neocortical neurones causes GABAA …