The limitations of angiotensin-converting-enzyme (ACE) inhibitors and the role of
angiotensin II-receptor blockers (ARBs) in the treatment of hypertension, heart failure, and …

One possible intervention to interrupt the deleterious effects of the renin-angiotensin system
is suppression of angiotensin II (Ang II) formation by inhibition of angiotensin-converting …

Losartan (COZAARΟχιρχ†) is the prototype of a new class of potent and selective
angiotensin II (AII) type 1 (AT1) receptor antagonists with the largest published preclinical …

Angiotensin‐converting enzyme inhibitors and angiotensin receptor blockers are commonly
prescribed for the management of hypertension. In addition, each of these drug classes has …

The renin-angiotensin-aldosterone system (RAAS) is activated in hypertension, cardiac and
renal disease and is attributed as a major factor in the morbidity and mortality associated …

Activation of the renin-angiotensin-aldosterone system (RAAS) in left ventricular systolic
dysfunction is a critically important determinant in the pathophysiologic processes that lead …

OBJECTIVE: To evaluate the safety, tolerability, and efficacy of chronic combination therapy
with an angiotensin-converting enzyme (ACE) inhibitor and an angiotensin II receptor …

Angiotensin converting enzyme inhibitors and angiotensin receptor blockers are commonly
used to treat hypertension and/or a range of progressive end‐organ diseases. The success …

Numerous clinical trials have highlighted the role of the renin‐angiotensin‐aldosterone
(RAA) system in the development and progression of heart failure. Over 30 randomized …

METHODS Studies were identified by searching MEDLINE within yearparameters of 1970
and 2001 using the terms angiotensin-convertingenzyme inhibitor, angiotensin-receptor …