Epidemiological studies have indicated an association between statin use and reduced
incidence of colorectal cancer (CRC), and work in preclinical models has demonstrated a …

The liver is a common primary site not only for tumorigenesis, but also for cancer metastasis.
Advanced cancer patients with liver metastases also show reduced response rates and …

Simple Summary While both the fields of cancer metastasis research and cancer
immunology have been heavily investigated, their combination—the immunology of …

Colorectal cancer (CRC) is the second-most common malignant disease worldwide, and
metastasis is the main culprit of CRC-related death. Metachronous metastases remain to be …

Metastasis is the main reason for the high mortality rate of colorectal cancer (CRC) patients.
Despite the whole improvement in the field of cancer medicine, the treatment options for the …

Lipid rafts are highly ordered membrane domains that are enriched in cholesterol and
glycosphingolipids and serve as major platforms for signal transduction. Cell detachment …

Simple Summary Extramedullary multiple myeloma (EMM) is a rare and aggressive subtype
of multiple myeloma which is associated with a poor prognosis. Here, we used mass …

Simple Summary We discovered a novel association of cancer and stemness. In particular,
we demonstrate an MACC1—LGR5 link by transcriptional regulation of the crucial stemness …

The human microbiome has recently emerged as a focal point in cancer research,
specifically in anti-tumor immunity, immunotherapy, and chemotherapy. This review explores …

Simple Summary High metastasis-associated in colon cancer 1 (MACC1) expression is
associated with metastasis, tumor cell migration, and increased proliferation in colorectal …