B cells, plasma cells and antibody repertoires in the tumour microenvironment

GV Sharonov, EO Serebrovskaya… - Nature Reviews …, 2020 - nature.com
Recent data show that B cells and plasma cells located in tumours or in tumour-draining
lymph nodes can have important roles in shaping antitumour immune responses. In tumour …

Progress and prospects of early detection in lung cancer

S Blandin Knight, PA Crosbie, H Balata… - Open …, 2017 - royalsocietypublishing.org
Lung cancer is the leading cause of cancer-related death in the world. It is broadly divided
into small cell (SCLC, approx. 15% cases) and non-small cell lung cancer (NSCLC, approx …

[HTML][HTML] Biomarkers in lung cancer screening: achievements, promises, and challenges

LM Seijo, N Peled, D Ajona, M Boeri, JK Field… - Journal of Thoracic …, 2019 - Elsevier
The present review is an update of the research and development efforts regarding the use
of molecular biomarkers in the lung cancer screening setting. The two main unmet clinical …

Earlier diagnosis of lung cancer in a randomised trial of an autoantibody blood test followed by imaging

FM Sullivan, FS Mair, W Anderson… - European …, 2021 - Eur Respiratory Soc
The EarlyCDT-Lung test is a high-specificity blood-based autoantibody biomarker that could
contribute to predicting lung cancer risk. We report on the results of a phase IV biomarker …

[HTML][HTML] Non-small cell lung carcinoma (NSCLC): Implications on molecular pathology and advances in early diagnostics and therapeutics

H Padinharayil, J Varghese, MC John, GK Rajanikant… - Genes & …, 2023 - Elsevier
Continuous revision of the histologic and stage-wise classification of lung cancer by the
World Health Organization (WHO) provides the foundation for therapeutic advances by …

Lung cancer screening

LT Tanoue, NT Tanner, MK Gould… - American journal of …, 2015 - atsjournals.org
The United States Preventive Services Task Force recommends lung cancer screening with
low-dose computed tomography (LDCT) in adults of age 55 to 80 years who have a 30 pack …

The liquid biopsy for lung cancer: state of the art, limitations and future developments

D Di Capua, D Bracken-Clarke, K Ronan, AM Baird… - Cancers, 2021 - mdpi.com
Simple Summary During the development and progression of lung tumors, processes such
as necrosis and vascular invasion shed tumor cells or cellular components into various fluid …

Molecular and circulating biomarkers of gastric cancer

W Jelski, B Mroczko - International Journal of Molecular Sciences, 2022 - mdpi.com
Gastric cancer (GC)—a common tumor that affects humans worldwide—is highly malignant
with a poor prognosis. GC is frequently not diagnosed until a relatively advanced stage …

[HTML][HTML] Validation of the SHOX2/PTGER4 DNA methylation marker panel for plasma-based discrimination between patients with malignant and nonmalignant lung …

G Weiss, A Schlegel, D Kottwitz, T König… - Journal of Thoracic …, 2017 - Elsevier
Introduction Low-dose computed tomography (LDCT) is used for screening for lung cancer
(LC) in high-risk patients in the United States. The definition of high risk and the impact of …

[HTML][HTML] Advances in lung cancer screening and early detection

C Li, H Wang, Y Jiang, W Fu, X Liu… - Cancer biology & …, 2022 - ncbi.nlm.nih.gov
Lung cancer is associated with a heavy cancer-related burden in terms of patients' physical
and mental health worldwide. Two randomized controlled trials, the US-National Lung …