Translational control of covid-19 and its therapeutic implication
D Zhang, L Zhu, Y Wang, P Li, Y Gao - Frontiers in immunology, 2022 - frontiersin.org
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent
of COVID-19, which has broken out worldwide for more than two years. However, due to …
of COVID-19, which has broken out worldwide for more than two years. However, due to …
[HTML][HTML] CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.
M Gupta, CM Azumaya, M Moritz, S Pourmal… - Research …, 2021 - ncbi.nlm.nih.gov
Abstract The SARS-CoV-2 protein Nsp2 has been implicated in a wide range of viral
processes, but its exact functions, and the structural basis of those functions, remain …
processes, but its exact functions, and the structural basis of those functions, remain …
Plasma cell-free RNA characteristics in COVID-19 patients
Y Wang, J Li, L Zhang, HX Sun, Z Zhang, J Xu… - Genome …, 2022 - genome.cshlp.org
The pathogenesis of COVID-19 is still elusive, which impedes disease progression
prediction, differential diagnosis, and targeted therapy. Plasma cell-free RNAs (cfRNAs) …
prediction, differential diagnosis, and targeted therapy. Plasma cell-free RNAs (cfRNAs) …
Computational analysis of SARS-CoV-2 and SARS-like coronavirus diversity in human, bat and pangolin populations
In 2019, a novel coronavirus, SARS-CoV-2/nCoV-19, emerged in Wuhan, China, and has
been responsible for the current COVID-19 pandemic. The evolutionary origins of the virus …
been responsible for the current COVID-19 pandemic. The evolutionary origins of the virus …
Genome-wide analysis of codon usage patterns of SARS-CoV-2 virus reveals global heterogeneity of COVID-19
The ongoing outbreak of coronavirus disease COVID-19 is significantly implicated by global
heterogeneity in the genome organization of severe acute respiratory syndrome coronavirus …
heterogeneity in the genome organization of severe acute respiratory syndrome coronavirus …
Distinct responses to rare codons in select Drosophila tissues
SR Allen, RK Stewart, M Rogers, IJ Ruiz, E Cohen… - Elife, 2022 - elifesciences.org
Codon usage bias has long been appreciated to influence protein production. Yet, relatively
few studies have analyzed the impacts of codon usage on tissue-specific mRNA and protein …
few studies have analyzed the impacts of codon usage on tissue-specific mRNA and protein …
Base composition and host adaptation of the SARS-CoV-2: insight from the codon usage perspective
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been
spreading rapidly all over the world and has raised grave concern globally. The present …
spreading rapidly all over the world and has raised grave concern globally. The present …
[HTML][HTML] Analysis of SARS-CoV-2 synonymous codon usage evolution throughout the COVID-19 pandemic
Abstract SARS-CoV-2, the seventh coronavirus known to infect humans, can cause severe
life-threatening respiratory pathologies. To better understand SARS-CoV-2 evolution …
life-threatening respiratory pathologies. To better understand SARS-CoV-2 evolution …
Molecular features similarities between SARS-CoV-2, SARS, MERS and key human genes could favour the viral infections and trigger collateral effects
LL Maldonado, AM Bertelli, L Kamenetzky - Scientific Reports, 2021 - nature.com
In December 2019, rising pneumonia cases caused by a novel β-coronavirus (SARS-CoV-2)
occurred in Wuhan, China, which has rapidly spread worldwide, causing thousands of …
occurred in Wuhan, China, which has rapidly spread worldwide, causing thousands of …
Large-scale analysis of SARS-CoV-2 synonymous mutations reveals the adaptation to the human codon usage during the virus evolution
Many large national and transnational studies have been dedicated to the analysis of
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) genome, most of which …
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) genome, most of which …