Glioblastoma multiforme (GBM) is the most common adult primary brain tumor. The standard
clinical treatment of GBM includes a maximal surgical resection followed by concomitant …

Background Carbon dioxide (CO2), traditionally viewed as a mere byproduct of cellular
respiration, plays a multifaceted role in human physiology beyond simple elimination …

ABSTRACT FLASH radiotherapy (FLASH-RT) is a new modality of radiotherapy that delivers
doses with ultra-high dose rates. The FLASH effect was defined as the ability of FLASH-RT …

Ultra-high dose rate radiotherapy with electrons and protons has shown potential for cancer
treatment by effectively targeting tumors while sparing healthy tissues (FLASH effect). This …

FLASH radiotherapy is attracting increasing interest because it maintains tumor control while
inflicting less damage to normal tissues compared to conventional radiotherapy. This …

FLASH ultra-high dose rate radiotherapy (RT) can effectively exert the protective effect on
normal tissue and reduce the risk of treatment-related toxicity, without compromising the …

Glioblastoma remains a fatal diagnosis despite continuous efforts to improve upon the
current standard backbone management paradigm of surgery, radiation therapy, systemic …

Background and purpose This study aimed to investigate the radiochemical oxygen
depletion (ROD) in vivo by directly measuring oxygen levels in various mouse tissues during …

A novel means of applying radiotherapy in cancer treatment is the application of a radiation
dose at a very high intensity for a very short time in FLASH radiotherapy (FLASH-RT). This …

To the Editor: Radiotherapy is an essential component of modern cancer treatment
modalities, used by nearly 70% of all individuals diagnosed with cancer. However …