Recent advancements and developments in search of anti-tuberculosis agents: a quinquennial update and future directions
Tuberculosis (TB) has been considered as the highly chronic, contagious and infectious
disorder caused by Mycobacterium tuberculosis (Mtb). Every year more than 10 million …
disorder caused by Mycobacterium tuberculosis (Mtb). Every year more than 10 million …
New potential drug leads against MDR-MTB: A short review
Multidrug resistant Mycobacterium tuberculosis (MDR-MTB) infections have created a critical
health problem globally. The appalling rise in drug resistance to all the current therapeutics …
health problem globally. The appalling rise in drug resistance to all the current therapeutics …
[HTML][HTML] Culturable Streptomyces spp. from high-altitude, oligotrophic North Western Himalaya: a comprehensive study on the diversity, bioactivity and insights into …
AM Bhat, A Hussain, QP Hassan… - FEMS Microbiology …, 2024 - academic.oup.com
The increasing global concern of antimicrobial resistance and shortage of new
antimicrobials necessitates exploring untapped terrestrial environments for new bioactive …
antimicrobials necessitates exploring untapped terrestrial environments for new bioactive …
[HTML][HTML] Dinactin from a new producer, Streptomyces badius gz-8, and its antifungal activity against the rubber anthracnose fungus Colletotrichum gloeosporioides
K Zhang, L Gu, Y Zhang, Z Liu, X Li - Microbiological Research, 2020 - Elsevier
Colletotrichum gloeosporioides is a main cause of rubber anthracnose, which results in very
large losses for the natural rubber industry. In this study, an actinomycete strain gz-8 was …
large losses for the natural rubber industry. In this study, an actinomycete strain gz-8 was …
[HTML][HTML] In vitro antimycobacterial activity and interaction profiles of diarylthiourea-copper (II) complexes with antitubercular drugs against Mycobacterium tuberculosis …
A Bielenica, A Głogowska, E Augustynowicz-Kopeć… - Tuberculosis, 2023 - Elsevier
The activity of several halogenated copper (II) complexes of 4-chloro-3-nitrophenylthiourea
derivatives has been tested against Mycobacterium tuberculosis strains and strains of non …
derivatives has been tested against Mycobacterium tuberculosis strains and strains of non …
[HTML][HTML] Assessment of the efficacy of clofazimine alone and in combination with primary agents against Mycobacterium tuberculosis in vitro
SA Mashele, HC Steel, MT Matjokotja… - Journal of Global …, 2022 - Elsevier
Objectives The chemotherapeutic regimens of patients with drug-susceptible (DS)-
tuberculosis (TB) comprise four primary anti-TB drugs: rifampicin (RMP), isoniazid (INH) …
tuberculosis (TB) comprise four primary anti-TB drugs: rifampicin (RMP), isoniazid (INH) …
[HTML][HTML] Enniatin A1, A Natural Compound with Bactericidal Activity against Mycobacterium tuberculosis In Vitro
G Wang, W Dong, H Lu, W Lu, J Feng, X Wang, H Chen… - Molecules, 2019 - mdpi.com
Background: Tuberculosis remains a global disease that poses a serious threat to human
health, but there is lack of new and available anti-tuberculosis agents to prevent the …
health, but there is lack of new and available anti-tuberculosis agents to prevent the …
Evaluation of a novel inhibitor of aspartate semialdehyde dehydrogenase as a potent antitubercular agent against Mycobacterium tuberculosis
R Yang, W Cao, S Liu, Q Li, Y Sun, C Liang… - The Journal of …, 2022 - nature.com
The in vitro activity of IMB-XMA0038, a novel inhibitor targeting Mycobacterial tuberculosis
(Mtb) aspartate semialdehyde dehydrogenase, was evaluated. Minimum inhibitory …
(Mtb) aspartate semialdehyde dehydrogenase, was evaluated. Minimum inhibitory …
[HTML][HTML] Antimicrobials: shift from conventional to extreme sources
AM Bhat, QP Hassan, A Hussain - … -Diversity, Applications and …, 2022 - intechopen.com
Antimicrobials-the chemical substances that inhibit the growth of microorganisms and stop
their multiplication are immensely useful in the context of pathogenic microorganisms where …
their multiplication are immensely useful in the context of pathogenic microorganisms where …
Comparative genomics studies provide insights into the taxonomic classification and secondary metabolic potential of five bioactive Streptomyces species isolated …
AM Bhat, MA Haneen, A Hussain, G Sharma… - bioRxiv, 2024 - biorxiv.org
The linear genome of genus Streptomyces members has the potential to encode diverse
and novel biosynthetic gene clusters of invaluable antimicrobial and therapeutic …
and novel biosynthetic gene clusters of invaluable antimicrobial and therapeutic …