Polysorbates 20 and 80 used in the formulation of protein biotherapeutics: structure and degradation pathways
BA Kerwin - Journal of pharmaceutical sciences, 2008 - Elsevier
ABSTRACT Polysorbates 20 and 80 (Tween® 20 and Tween® 80) are used in the
formulation of biotherapeutic products for both preventing surface adsorption and as …
formulation of biotherapeutic products for both preventing surface adsorption and as …
Trends on analytical characterization of polysorbates and their degradation products in biopharmaceutical formulations
A Martos, W Koch, W Jiskoot, K Wuchner… - Journal of …, 2017 - Elsevier
Among many other applications, polysorbates (PSs) are used as the most common
surfactants in biopharmaceutical products in particular to protect proteins against interfacial …
surfactants in biopharmaceutical products in particular to protect proteins against interfacial …
Antigen retrieval and clearing for whole-organ immunofluorescence by FLASH
Advances in light-sheet and confocal microscopy now allow imaging of cleared large
biological tissue samples and enable the 3D appreciation of cell and protein localization in …
biological tissue samples and enable the 3D appreciation of cell and protein localization in …
[HTML][HTML] Molecular mechanism of membrane permeabilization by the peptide antibiotic surfactin
C Carrillo, JA Teruel, FJ Aranda, A Ortiz - Biochimica et Biophysica Acta …, 2003 - Elsevier
Surfactin, an acidic lipopeptide produced by various strains of Bacillus subtilis, behaves as a
very powerful biosurfactant and possesses several other interesting biological activities. This …
very powerful biosurfactant and possesses several other interesting biological activities. This …
Partitioning of Thy-1, GM1, and cross-linked phospholipid analogs into lipid rafts reconstituted in supported model membrane monolayers
C Dietrich, ZN Volovyk, M Levi… - Proceedings of the …, 2001 - National Acad Sciences
As shown earlier, raft-like domains resembling those thought to be present in natural cell
membranes can be formed in supported planar lipid monolayers. These liquid-ordered …
membranes can be formed in supported planar lipid monolayers. These liquid-ordered …
Anionic micelles and vesicles induce tau fibrillization in vitro
CN Chirita, M Necula, J Kuret - Journal of Biological Chemistry, 2003 - ASBMB
Alzheimer's disease is defined in part by the intraneuronal accumulation of filaments
comprised of the microtubule-associated protein tau. In vitro, fibrillization of recombinant tau …
comprised of the microtubule-associated protein tau. In vitro, fibrillization of recombinant tau …
[图书][B] Introduction to biological membranes
MK Jain, RC Wagner - 1988 - core.ac.uk
The amount of information generated by intensive studies of biological membranes over the
past years is such that a comprehensive treatise is now a major undertaking. This new …
past years is such that a comprehensive treatise is now a major undertaking. This new …
[HTML][HTML] Oxidation of polysorbates–An underestimated degradation pathway?
J Weber, J Buske, K Mäder, P Garidel… - International Journal of …, 2023 - Elsevier
To ensure the stability of biologicals over their entire shelf-life, non-ionic surface-active
compounds (surfactants) are added to protect biologics from denaturation and particle …
compounds (surfactants) are added to protect biologics from denaturation and particle …
Protein sizing on a microchip
We have developed a microfabricated analytical device on a glass chip that performs a
protein sizing assay, by integrating the required separation, staining, virtual destaining, and …
protein sizing assay, by integrating the required separation, staining, virtual destaining, and …
Nanoparticles and surfaces presenting antifungal, antibacterial and antiviral properties
D Botequim, J Maia, MMF Lino, LMF Lopes… - Langmuir, 2012 - ACS Publications
Here, we present new antimicrobial nanoparticles based on silica nanoparticles (SNPs)
coated with a quaternary ammonium cationic surfactant, didodecyldimethylammonium …
coated with a quaternary ammonium cationic surfactant, didodecyldimethylammonium …