Manufacturing of hydrogel biomaterials with controlled mechanical properties for tissue engineering applications

A Vedadghavami, F Minooei, MH Mohammadi… - Acta biomaterialia, 2017 - Elsevier
Hydrogels have been recognized as crucial biomaterials in the field of tissue engineering,
regenerative medicine, and drug delivery applications due to their specific characteristics …

Niche stiffness underlies the ageing of central nervous system progenitor cells

M Segel, B Neumann, MFE Hill, IP Weber, C Viscomi… - Nature, 2019 - nature.com
Ageing causes a decline in tissue regeneration owing to a loss of function of adult stem cell
and progenitor cell populations. One example is the deterioration of the regenerative …

Advances in micropipette aspiration: applications in cell biomechanics, models, and extended studies

B González-Bermúdez, GV Guinea, GR Plaza - Biophysical Journal, 2019 - cell.com
With five decades of sustained application, micropipette aspiration has enabled a wide
range of biomechanical studies in the field of cell mechanics. Here, we provide an update on …

How deeply cells feel: methods for thin gels

A Buxboim, K Rajagopal, B Andre'EX… - Journal of Physics …, 2010 - iopscience.iop.org
Tissue cells lack the ability to see or hear but have evolved mechanisms to feel into their
surroundings and sense a collective stiffness. A cell can even sense the effective stiffness of …

Mapping microbubble viscosity using fluorescence lifetime imaging of molecular rotors

NA Hosny, G Mohamedi… - Proceedings of the …, 2013 - National Acad Sciences
Encapsulated microbubbles are well established as highly effective contrast agents for
ultrasound imaging. There remain, however, some significant challenges to fully realize the …

Migration and 3D traction force measurements inside compliant microchannels

A Afthinos, K Bera, J Chen, A Ozcelikkale… - Nano …, 2022 - ACS Publications
Cells migrate in vivo through channel-like tracks. While polydimethylsiloxane devices
emulate such tracks in vitro, their channel walls are impermeable and have …

Mapping elasticity moduli of atherosclerotic plaque in situ via atomic force microscopy

P Tracqui, A Broisat, J Toczek, N Mesnier… - Journal of structural …, 2011 - Elsevier
Several studies have suggested that evolving mechanical stresses and strains drive
atherosclerotic plaque development and vulnerability. Especially, stress distribution in the …

Hydrogel microcapsules with a thin oil layer: smart triggered release via diverse stimuli

HS Jeong, E Kim, C Nam, Y Choi… - Advanced Functional …, 2021 - Wiley Online Library
A hydrogel microcapsule with an intermediate thin oil layer is presented to achieve smart
release of a broad range of cargoes triggered via diverse stimuli. A microfluidic technique is …

An extended relationship for the characterization of Young's modulus and Poisson's ratio of tunable polyacrylamide gels

T Boudou, J Ohayon, C Picart, P Tracqui - Biorheology, 2006 - content.iospress.com
Substrates with tunable mechanical properties are crucial for the study of cellular processes,
and polyacrylamide gels (PAGs) are frequently used in this context. Several experimental …

[PDF][PDF] Mechanical characterisation of hydrogels for tissue engineering applications

M Ahearne, Y Yang, KK Liu - Topics in tissue Engineering, 2008 - oulu.fi
H ydrogels have been extensively investigated for use as constructs to engineer tissues in-
vitro. Among the principal limitations with using hydrogels for engineering tissues are their …