[HTML][HTML] Harnessing tissue-derived extracellular vesicles for osteoarthritis theranostics

B Yin, J Ni, CE Witherel, M Yang, JA Burdick, C Wen… - Theranostics, 2022 - ncbi.nlm.nih.gov
Osteoarthritis (OA) is a prevalent chronic whole-joint disease characterized by low-grade
systemic inflammation, degeneration of joint-related tissues such as articular cartilage, and …

[HTML][HTML] Role of hypoxia preconditioning in therapeutic potential of mesenchymal stem-cell-derived extracellular vesicles

V Pulido-Escribano, B Torrecillas-Baena… - World Journal of Stem …, 2022 - ncbi.nlm.nih.gov
The use of mesenchymal stem-cells (MSC) in cell therapy has received considerable
attention because of their properties. These properties include high expansion and …

[HTML][HTML] Production and utility of extracellular vesicles with 3D culture methods

M Casajuana Ester, RM Day - Pharmaceutics, 2023 - mdpi.com
In recent years, extracellular vesicles (EVs) have emerged as promising biomarkers, cell-
free therapeutic agents, and drug delivery carriers. Despite their great clinical potential, poor …

[HTML][HTML] Nanovesicles-mediated drug delivery for oral bioavailability enhancement

Y Ren, L Nie, S Zhu, X Zhang - International Journal of …, 2022 - ncbi.nlm.nih.gov
Bioavailability is an eternal topic that cannot be circumvented by peroral drug delivery.
Adequate blood drug exposure after oral administration is a prerequisite for effective …

Advances in mesenchymal stem/stromal cell-based therapy and their extracellular vesicles for skin wound healing

MJ Saadh, AA Ramírez-Coronel, RS Saini… - Human Cell, 2023 - Springer
Wound healing is a dynamic and complicated process containing overlapping phases.
Presently, definitive therapy is not available, and the investigation into optimal wound care is …

[HTML][HTML] Dental mesenchymal stem cell secretome: An intriguing approach for neuroprotection and neuroregeneration

A Gugliandolo, E Mazzon - International journal of molecular sciences, 2021 - mdpi.com
Mesenchymal stem cells (MSCs) are known for their beneficial effects and regenerative
potential. In particular, dental-derived MSCs have the advantage of easier accessibility and …

Extracellular Vesicles in Atherosclerosis: State of the Art

W Olejarz, K Sadowski, K Radoszkiewicz - International Journal of …, 2023 - mdpi.com
Atherosclerosis is a chronic inflammatory disease driven by lipid accumulation in the
arteries, leading to narrowing and thrombosis that causes mortality. Emerging evidence has …

[HTML][HTML] 3D culture and interferon-γ Priming modulates characteristics of mesenchymal stromal/stem cells by modifying the expression of both intracellular and …

M Bulati, A Gallo, G Zito, R Busà, G Iannolo, N Cuscino… - Biology, 2023 - mdpi.com
Simple Summary With the aim of improving the therapeutic potential of mesenchymal
stromal/stem cells (MSCs), we analyzed miRNA expression to investigate the effects of …

Detection of Circulating Tumor Cells and Epithelial Progenitor Cells: A Comprehensive Study

S Fuloria, V Subramaniyan, G Gupta… - Journal of …, 2023 - dl.begellhouse.com
Technological advancement to enhance tumor cells (TC) has allowed discovery of various
cellular bio-markers: cancer stem cells (CSC), circulating tumor cells (CTC), and endothelial …

The Effect of Different Frequencies of Pulsed Electromagnetic Fields on Cartilage Repair of Adipose Mesenchymal Stem Cell–Derived Exosomes in Osteoarthritis

Y Xu, Q Wang, XX Wang, XN Xiang, JL Peng… - Cartilage, 2022 - journals.sagepub.com
Background The intra-articular injection of mesenchymal stem cell (MSC)-derived exosomes
has already been proved to reverse osteoarthritic cartilage degeneration. Pulsed …