Non-coding RNAs: Epigenetic regulators of bone development and homeostasis
Non-coding RNAs (ncRNAs) have evolved in eukaryotes as epigenetic regulators of gene
expression. The most abundant regulatory ncRNAs are the 20–24 nt small microRNAs …
expression. The most abundant regulatory ncRNAs are the 20–24 nt small microRNAs …
smiFISH and FISH-quant–a flexible single RNA detection approach with super-resolution capability
N Tsanov, A Samacoits, R Chouaib… - Nucleic acids …, 2016 - academic.oup.com
Single molecule FISH (smFISH) allows studying transcription and RNA localization by
imaging individual mRNAs in single cells. We present smiFISH (single molecule …
imaging individual mRNAs in single cells. We present smiFISH (single molecule …
[HTML][HTML] microRNA-guided diagnostics in clinical samples
miRNA-guided diagnostics is a powerful molecular approach for evaluating clinical samples
through miRNA detection and/or visualization. To date, this approach has been successfully …
through miRNA detection and/or visualization. To date, this approach has been successfully …
Long non-coding RNA C2dat1 regulates CaMKIIδ expression to promote neuronal survival through the NF-κB signaling pathway following cerebral ischemia
Q Xu, F Deng, Z Xing, Z Wu, B Cen, S Xu, Z Zhao… - Cell death & …, 2016 - nature.com
Increasing evidence has demonstrated a significant role of long non-coding RNAs
(lncRNAs) in diverse biological processes. However, their functions in cerebral ischemia …
(lncRNAs) in diverse biological processes. However, their functions in cerebral ischemia …
[HTML][HTML] Promoter and enhancer RNAs regulate chromatin reorganization and activation of miR-10b/HOXD locus, and neoplastic transformation in glioma
E Deforzh, EJ Uhlmann, E Das, A Galitsyna, R Arora… - Molecular cell, 2022 - cell.com
Summary miR-10b is silenced in normal neuroglial cells of the brain but commonly activated
in glioma, where it assumes an essential tumor-promoting role. We demonstrate that the …
in glioma, where it assumes an essential tumor-promoting role. We demonstrate that the …
Full-length mRNA sequencing uncovers a widespread coupling between transcription initiation and mRNA processing
Background The multifaceted control of gene expression requires tight coordination of
regulatory mechanisms at transcriptional and post-transcriptional level. Here, we studied the …
regulatory mechanisms at transcriptional and post-transcriptional level. Here, we studied the …
MALAT1: a regulator of inflammatory cytokines in diabetic complications
AD Gordon, S Biswas, B Feng… - … , diabetes & metabolism, 2018 - Wiley Online Library
Summary Objectives and Design In this study, we examined the role of MALAT 1, a highly
conserved nuclear long non‐coding RNA molecule, in chronic diabetic complications …
conserved nuclear long non‐coding RNA molecule, in chronic diabetic complications …
[HTML][HTML] Single molecule fluorescence in situ hybridisation for quantitating post-transcriptional regulation in Drosophila brains
RNA in situ hybridization is a powerful method to investigate post-transcriptional regulation,
but analysis of intracellular mRNA distributions in thick, complex tissues like the brain poses …
but analysis of intracellular mRNA distributions in thick, complex tissues like the brain poses …
Reference genes for quantitative Arabidopsis single molecule RNA fluorescence in situ hybridization
Subcellular mRNA quantities and spatial distributions are fundamental for driving gene
regulatory programmes. Single molecule RNA fluorescence in situ hybridization (smFISH) …
regulatory programmes. Single molecule RNA fluorescence in situ hybridization (smFISH) …
Stellaris® RNA Fluorescence In Situ Hybridization for the Simultaneous Detection of Immature and Mature Long Noncoding RNAs in Adherent Cells
AV Orjalo, HE Johansson - Long Non-Coding RNAs: Methods and …, 2016 - Springer
RNA fluorescence in situ hybridization (FISH), long an indispensable tool for the detection
and localization of RNA, is becoming an increasingly important complement to other gene …
and localization of RNA, is becoming an increasingly important complement to other gene …