Peripheral and central effects of melatonin on blood pressure regulation

O Pechanova, L Paulis, F Simko - International journal of molecular …, 2014 - mdpi.com
The pineal hormone, melatonin (N-acetyl-5-methoxytryptamine), shows potent receptor-
dependent and-independent actions, which participate in blood pressure regulation. The …

Anti-inflammatory effects of melatonin in obesity and hypertension

NJ Prado, L Ferder, W Manucha, ER Diez - Current hypertension reports, 2018 - Springer
Abstract Purpose of Review Here, we review the known relations between hypertension and
obesity to inflammation and postulate the endogenous protective effect of melatonin and its …

[HTML][HTML] Melatonin protects diabetic heart against ischemia-reperfusion injury, role of membrane receptor-dependent cGMP-PKG activation

L Yu, W Di, X Dong, Z Li, Y Zhang, X Xue, Y Xu… - … et Biophysica Acta (BBA …, 2018 - Elsevier
It has been demonstrated that the anti-oxidative and cardioprotective effects of melatonin
are, at least in part, mediated by its membrane receptors. However, the direct downstream …

Melatonin and the metabolic syndrome: a tool for effective therapy in obesity‐associated abnormalities?

F Nduhirabandi, EF du Toit, A Lochner - Acta physiologica, 2012 - Wiley Online Library
The metabolic syndrome (M et S) is a cluster of metabolic abnormalities associated with
increased risk for cardiovascular diseases. Apart from its powerful antioxidant properties, the …

Melatonin for the management of preeclampsia: a review

A Langston-Cox, SA Marshall, D Lu, KR Palmer… - Antioxidants, 2021 - mdpi.com
Preeclampsia is a disease specific to pregnancy characterised by new-onset hypertension
with maternal organ dysfunction and/or fetal growth restriction. It remains a major cause of …

Potential utility of melatonin in preeclampsia, intrauterine fetal growth retardation, and perinatal asphyxia

L Marseglia, G D'Angelo, S Manti… - Reproductive …, 2016 - journals.sagepub.com
Aim: Reactive oxygen species play an important role in the pathogenesis of several
diseases during gestation and the perinatal period. During pregnancy, increased oxygen …

Caffeine increases mitochondrial function and blocks melatonin signaling to mitochondria in Alzheimer's mice and cells

N Dragicevic, V Delic, C Cao, N Copes, X Lin… - …, 2012 - Elsevier
Caffeine and melatonin have been shown to protect the Swedish mutant amyloid precursor
protein (APPsw) transgenic mouse model of Alzheimer's disease from cognitive dysfunction …

Melatonin suppresses milk fat synthesis by inhibiting the mTOR signaling pathway via the MT 1 receptor in bovine mammary epithelial cells

Y Wang, W Guo, H Xu, K Tang, L Zan… - Journal of pineal …, 2019 - Wiley Online Library
Milk fat content is an important criterion for assessing milk quality and is one of the main
target traits of dairy cattle breeding. Recent studies have shown the importance of melatonin …

Neuromodulatory role of melatonin in retinal information processing

H Huang, Z Wang, SJ Weng, XH Sun… - Progress in retinal and eye …, 2013 - Elsevier
The neurohormone melatonin is implicated in a variety of physiological processes. In the
retina, a major source for melatonin production, melatonin is involved in modulation of …

Melatonin modulates the functions of porcine granulosa cells via its membrane receptor MT2 in vitro

YM He, HH Deng, MH Shi, BM Bodinga… - Animal reproduction …, 2016 - Elsevier
Abstract Melatonin (N-acetyl-5-methoxytryptamine) is documented as a hormone involved in
the circadian regulation of physiological and neuroendocrine function in mammals. Herein …