Selective covalent protein immobilization: strategies and applications

LS Wong, F Khan, J Micklefield - Chemical reviews, 2009 - ACS Publications
The development and applications of site-selective protein immobilization have undergone
significant advances in recent years. Notably the recent fusion of synthetic chemistry and …

Protein microarray technology

DA Hall, J Ptacek, M Snyder - Mechanisms of ageing and development, 2007 - Elsevier
Protein chips have emerged as a promising approach for a wide variety of applications
including the identification of protein–protein interactions, protein–phospholipid interactions …

Microfluidic chips for point‐of‐care immunodiagnostics

L Gervais, N De Rooij, E Delamarche - Advanced materials, 2011 - Wiley Online Library
We might be at the turning point where research in microfluidics undertaken in academia
and industrial research laboratories, and substantially sponsored by public grants, may …

An extracellular matrix microarray for probing cellular differentiation

CJ Flaim, S Chien, SN Bhatia - Nature methods, 2005 - nature.com
We present an extracellular matrix (ECM) microarray platform for the culture of patterned
cells atop combinatorial matrix mixtures. This platform enables the study of differentiation in …

Display technologies: application for the discovery of drug and gene delivery agents

A Sergeeva, MG Kolonin, JJ Molldrem… - Advanced drug delivery …, 2006 - Elsevier
Recognition of molecular diversity of cell surface proteomes in disease is essential for the
development of targeted therapies. Progress in targeted therapeutics requires establishing …

Solid supports for microarray immunoassays

W Kusnezow, JD Hoheisel - Journal of molecular recognition, 2003 - Wiley Online Library
Stimulated by the achievements of the first phase in genomics and the resulting need of
assigning functions to the acquired sequence information, novel formats of immunoassays …

Progress in protein and antibody microarray technology

P Angenendt - Drug discovery today, 2005 - Elsevier
The success of genome sequencing projects has led to a shift from the description of single
molecules to the characterisation of complex samples. At the same time, there is growing …

Early sepsis diagnosis via protein and miRNA biomarkers using a novel point-of-care photonic biosensor

N Fabri-Faja, O Calvo-Lozano, P Dey, RA Terborg… - Analytica chimica …, 2019 - Elsevier
Sepsis is a condition characterized by a severe stage of blood-infection often leading to
tissue damage, organ failure and finally death. Fast diagnosis and identification of the sepsis …

Multiplexed sandwich assays in microarray format

UB Nielsen, BH Geierstanger - Journal of immunological methods, 2004 - Elsevier
Antibody arrays have evolved into powerful tools for quantifying proteins and qualifying their
state of activation in complex biological samples. This level of analysis holds tremendous …

Methods and applications of antibody microarrays in cancer research

BB Haab - Proteomics, 2003 - Wiley Online Library
Antibody microarrays have great potential for significant value in biological research. Cancer
research in particular could benefit from the unique experimental capabilities of this …