Ca2+ is one of the most universal and versatile signaling molecules and is involved in
almost every aspect of cellular processes. Viruses are adept at utilizing the universal Ca2+ …

Calcineurin is a serine-threonine–phosphatase that is expressed in a wide variety of tissues
and has particularly critical functions in neurons, cardiac and skeletal muscle cells, and …

The human T-cell leukemia virus type 1 (HTLV-1) is the cause of adult T-cell
leukemia/lymphoma as well as tropical spastic paraparesis/HTLV-1–associated myelopathy …

Human T lymphotropic viruses (HTLVs) are complex deltaretroviruses that do not contain a
proto-oncogene in their genome, yet are capable of transforming primary T lymphocytes …

Human T-cell lymphotropic virus type-1 (HTLV-1) has a large global burden and in some key
communities, such as Indigenous Australians living in remote areas, greater than 45% of …

We investigated the impact of monocytes, NK cells, and CD8+ T-cells in primary HTLV-1
infection by depleting cell subsets and exposing macaques to either HTLV-1 wild type …

Most cancers and leukemias are preceded by a prolonged period of clinical latency during
which cellular, chromosomal and molecular aberrations help move normal cell towards the …

Human T-cell lymphotropic virus type 1 (HTLV-1) establishes persistent infection and is
associated with lymphoproliferative or neurodegenerative diseases. As a complex retrovirus …

Human T-lymphotropic virus type 1 (HTLV-1) infection is associated with the clonal
expansion and transformation of mature T lymphocytes. While the mechanisms involved are …

HTLV-1 and HTLV-2 share broad similarities in their overall genetic organization and
expression pattern, but they differ substantially in their pathogenic properties. This review …