Xpert MTB/RIF and Xpert MTB/RIF Ultra for pulmonary tuberculosis and rifampicin resistance in adults
JS Zifodya, I Schiller, N Dendukuri… - Cochrane Database …, 2019 - cochranelibrary.com
Background Xpert MTB/RIF (Xpert MTB/RIF) and Xpert MTB/RIF Ultra (Xpert Ultra), the
newest version, are the only World Health Organization (WHO)‐recommended rapid tests …
newest version, are the only World Health Organization (WHO)‐recommended rapid tests …
Xpert Ultra versus Xpert MTB/RIF for pulmonary tuberculosis and rifampicin resistance in adults with presumptive pulmonary tuberculosis
JS Zifodya, JS Kreniske, I Schiller… - Cochrane Database …, 2021 - cochranelibrary.com
Background Xpert MTB/RIF and Xpert MTB/RIF Ultra (Xpert Ultra) are World Health
Organization (WHO)‐recommended rapid tests that simultaneously detect tuberculosis and …
Organization (WHO)‐recommended rapid tests that simultaneously detect tuberculosis and …
Feasibility, accuracy, and clinical effect of point-of-care Xpert MTB/RIF testing for tuberculosis in primary-care settings in Africa: a multicentre, randomised, controlled …
Summary Background The Xpert MTB/RIF test for tuberculosis is being rolled out in many
countries, but evidence is lacking regarding its implementation outside laboratories, ability to …
countries, but evidence is lacking regarding its implementation outside laboratories, ability to …
Do high rates of empirical treatment undermine the potential effect of new diagnostic tests for tuberculosis in high-burden settings?
In tuberculosis-endemic settings, patients are often treated empirically, meaning that they
are placed on treatment based on clinical symptoms or tests that do not provide a …
are placed on treatment based on clinical symptoms or tests that do not provide a …
False-positive Xpert MTB/RIF results in retested patients with previous tuberculosis: frequency, profile, and prospective clinical outcomes
ABSTRACT Globally, Xpert MTB/RIF (Xpert) is the most widely used PCR test for the
diagnosis of tuberculosis (TB). Positive results in previously treated patients, which are due …
diagnosis of tuberculosis (TB). Positive results in previously treated patients, which are due …
Determinants of PCR performance (Xpert MTB/RIF), including bacterial load and inhibition, for TB diagnosis using specimens from different body compartments
The determinants of Xpert MTB/RIF sensitivity, a widely used PCR test for the diagnosis of
tuberculosis (TB) are poorly understood. We compared culture time-to-positivity (TTP; a …
tuberculosis (TB) are poorly understood. We compared culture time-to-positivity (TTP; a …
Diagnosis of tuberculosis in HIV co‐infected individuals: current status, challenges and opportunities for the future
P Méndez‐Samperio - Scandinavian journal of immunology, 2017 - Wiley Online Library
Tuberculosis (TB) remains one of the most important causes of death among people co‐
infected with human immunodeficiency virus (HIV). The diagnosis of TB remains challenging …
infected with human immunodeficiency virus (HIV). The diagnosis of TB remains challenging …
Detecting active pulmonary tuberculosis with a breath test using nanomaterial-based sensors
MK Nakhleh, R Jeries, A Binder… - European …, 2014 - Eur Respiratory Soc
Detecting active tuberculosis (TB) remains a major global public health challenge [ 1]. The
tuberculin skin test does not distinguish latent from active TB [ 2]. The interferon-c release …
tuberculin skin test does not distinguish latent from active TB [ 2]. The interferon-c release …
Flexible bronchoscopy
RJ Miller, RF Casal, DR Lazarus… - Clinics in Chest …, 2018 - chestmed.theclinics.com
As we approach the 50th anniversary of the first commercially available flexible
bronchoscope, it is difficult to imagine diagnosing and treating diseases of the lungs and …
bronchoscope, it is difficult to imagine diagnosing and treating diseases of the lungs and …
Impact of the GeneXpert MTB/RIF technology on tuberculosis control
WS Stevens, L Scott, L Noble, N Gous… - Microbiology …, 2017 - Am Soc Microbiol
Molecular technology revolutionized the diagnosis of tuberculosis (TB) with a paradigm shift
to faster, more sensitive, clinically relevant patient care. The most recent molecular leader is …
to faster, more sensitive, clinically relevant patient care. The most recent molecular leader is …