The design of nanovaccines capable of triggering effective antitumor immunity requires an
understanding of how the immune system senses and responds to threats, including …

Breakthroughs in materials engineering have accelerated the progress of immunotherapy in
preclinical studies. The interplay of chemistry and materials has resulted in improved …

Active anti-cancer immune responses depend on efficient presentation of tumor antigens
and co-stimulatory signals by antigen-presenting cells (APCs). Therapy with autologous …

T cells are often referred to as the 'guided missiles' of our immune system because of their
capacity to traffic to and accumulate at sites of infection or disease, destroy infected or …

The versatility and nanoscale size have helped nanoparticles (NPs) improve the efficacy of
conventional cancer immunotherapy and opened up exciting approaches to combat cancer …

Biomimetic materials that target the immune system and generate an anti-tumor responses
hold promise in augmenting cancer immunotherapy. These synthetic materials can be …

Exciting developments in cancer nanomedicine include the engineering of nanocarriers to
deliver drugs locally to tumors, increasing efficacy and reducing off-target toxicity associated …

The immune system protects the body against a wide range of infectious diseases and
cancer by leveraging the efficiency of immune cells and lymphoid organs. Over the past …

Immunotherapy holds enormous promise to create a new outlook of cancer therapy by
eliminating tumors via activation of the immune system. In immunotherapy, polymeric …

T cell activation requires the coordination of a variety of signaling molecules including T cell
receptor-specific signals and costimulatory signals. Altering the composition and distribution …