Most drugs or the natural substances reputed to display some biological activity are
hydrophobic molecules that demonstrate low bioavailability regardless of their mode of …

Transglycosylation is the in-vivo or in-vitro process of transferring glycosyl groups from a
donor to an acceptor, which is usually performed by enzymatic reactions because of their …

An increasing number of transglycosylase-based processes provide access to
oligosaccharides or glycoconjugates, some of them reaching performance levels compatible …

(–)-Epigallocatechin gallate (EGCG), the predominant catechin (≥ 50%) in green tea
(Camellia sinensis), displays several bioactive properties but its stability and bioavailability …

Background Transglycosylation represents one of the most promising approaches for
obtaining novel glycosides, and plant phenols and polyphenols are emerging as one of the …

Glycans and glycosylated biomolecules are directly involved in almost every biological
process as well as the etiology of most major diseases. Hence, glycoscience knowledge is …

Leuconostoc lactis SBC001, isolated from chive, produces glucansucrase and synthesizes
oligosaccharides through its enzymatic activity. This study was conducted to optimize …

Despite the presence of a rutinosyl group at 3-OH, the aqueous solubility of the flavonoid
rutin is even lower than that of its aglycon quercetin. In this work, we describe a fast, simple …

The glycosylation of plant polyphenols may modulate their solubility and bioavailability and
protect these molecules from oxygen, light degradation, and during gastrointestinal transit. In …

Glycosylation of polyphenols may increase their aqueous solubility, stability, bioavailability
and pharmacological activity. Herein, we used a mutant of sucrose phosphorylase from …