Directional cell migration normally relies on a variety of external signals, such as chemical,
mechanical, or electrical, which instruct cells in which direction to move. Many of the major …

The mechanisms underpinning the formation of patterned cellular landscapes has been the
subject of extensive study as a fundamental problem of developmental biology. In most …

Axis formation in fish and amphibians typically begins with a prepattern of maternal gene
products. Annual killifish embryogenesis, however, challenges prepatterning models as …

Background Annual killifishes are adapted to surviving and reproducing over alternating dry
and wet seasons. During the dry season, all adults die and desiccation-resistant embryos …

While the chemical signals guiding neuronal migration and axon elongation have been
extensively studied, the influence of mechanical cues on these processes remains poorly …

Nothobranchius furzeri is emerging as an exciting vertebrate organism in the field of
biomedicine, developmental biology and ecotoxicology research. Its short generation time …

EpCAM and its close relative Trop2 are well-known cell surface markers of carcinoma, but
their potential role in cancer metastasis remains unclear. They are known, however, to …

Teleost eggs have evolved a highly derived early developmental pattern within vertebrates
as a result of the meroblastic cleavage pattern, giving rise to a polar stratified architecture …

A continuum description is built to characterize the stationary and transient deformations of
confluent tissues subject to heterogeneous activities. By defining a coarse-grained texture …

The mechanical microenvironment strongly affects cell state and decisions. Cell
mechanosensing has been described by a molecular clutch which gets progressively …