The development and repair of dentin are strictly regulated by hundreds of genes. Abnormal
dentin development is directly caused by gene mutations and dysregulation. Understanding …

Ascorbic acid (AA; vitamin C) plays a crucial role in the biosynthesis and secretion of
collagen to produce the organic matrix of hard tissues. Nevertheless, the detailed …

Introduction Vital pulp treatment (VPT) maintains tooth vitality with certain dental materials by
protecting pulp from noxious stimulation and promoting repair through enhancing cell …

The intricate and protracted process of dentin formation has been extensively explored,
thanks to the significant advancements facilitated by the use of animal models and related …

Dentinogenesis is a key process in tooth formation and is regulated by a series of pre-and
post-transcriptional regulations. N6-methyl-adenosine (m6A), which is the most prevalent …

Tissue regeneration is the preferred treatment for dentin and bone tissue defects. Dental
pulp stem cells (DPSCs) have been extensively studied for their use in tissue regeneration …

Human dental pulp stem cells (hDPSCs) are considered valuable for regenerative therapy.
Although glucose transporter 1 (GLUT1) is known to play a critical role in cell differentiation …

Conventional direct pulp-capping materials induce pulp cells to secrete various
biomolecules in pulp tissues that promote reparative dentin formation through induction of …

Direct pulp capping is performed to maintain the vitality of the exposed pulp by applying a
dressing material to facilitate reparative dentinogenesis as a biological seal. Osteoporosis …

Ascorbic acid (AA; vitamin C) plays a crucial role in the biosynthesis and secretion of
collagen to produce the organic matrix of hard tissues. Nevertheless, the detailed …