Responding quickly to unknown pathogens is crucial to stop uncontrolled spread of
diseases that lead to epidemics, such as the novel coronavirus, and to keep protective …

Despite considerable progress in genome-and proteome-based high-throughput screening
methods and in rational drug design, the increase in approved drugs in the past decade did …

The protein–protein interaction (PPI) network is crucial for cellular information processing
and decision-making. With suitable inputs, PPI networks drive the cells to diverse functional …

Abstract VirHostNet release 2.0 (http://virhostnet. prabi. fr) is a knowledgebase dedicated to
the network-based exploration of virus–host protein–protein interactions. Since the previous …

Many essential biological processes including cell regulation and signalling are mediated
through the assembly of protein complexes. Changes to protein-protein interaction (PPI) …

To study virus–host protein interactions, knowledge about viral and host protein
architectures and repertoires, their particular evolutionary mechanisms, and information on …

Viral infections often cause diseases by perturbing several cellular processes in the infected
host. Viral proteins target host proteins and either form new complexes or modulate the …

Autophagy is a conserved degradative pathway used as a host defense mechanism against
intracellular pathogens. However, several viruses can evade or subvert autophagy to insure …

Abstract Background Protein-protein interactions (PPIs) play a crucial role in initiating
infection in a host-pathogen system. Identification of these PPIs is important for …

Infectious diseases are still among the major and prevalent health problems, mostly
because of the drug resistance of novel variants of pathogens. Molecular interactions …