The role of host genetics in the immune response to SARS‐CoV‐2 and COVID‐19 susceptibility and severity
IG Ovsyannikova, IH Haralambieva… - Immunological …, 2020 - Wiley Online Library
This article provides a review of studies evaluating the role of host (and viral) genetics
(including variation in HLA genes) in the immune response to coronaviruses, as well as the …
(including variation in HLA genes) in the immune response to coronaviruses, as well as the …
The multifaceted roles of NLRP3-modulating proteins in virus infection
The innate immune response to viruses is critical for the correct establishment of protective
adaptive immunity. Amongst the many pathways involved, the NLRP3 [nucleotide-binding …
adaptive immunity. Amongst the many pathways involved, the NLRP3 [nucleotide-binding …
PAAN/MIF nuclease inhibition prevents neurodegeneration in Parkinson's disease
Parthanatos-associated apoptosis-inducing factor (AIF) nuclease (PAAN), also known as
macrophage migration inhibitor factor (MIF), is a member of the PD-D/E (X) K nucleases that …
macrophage migration inhibitor factor (MIF), is a member of the PD-D/E (X) K nucleases that …
[HTML][HTML] WISP1 and macrophage migration inhibitory factor in respiratory inflammation: Novel insights and therapeutic potentials for asthma and copd
ME Christopoulou, AJ Aletras… - International Journal of …, 2024 - mdpi.com
Recent advancements highlight the intricate interplay between the extracellular matrix
(ECM) and immune responses, notably in respiratory diseases such as asthma and Chronic …
(ECM) and immune responses, notably in respiratory diseases such as asthma and Chronic …
Blockade of MIF biological activity ameliorates house dust mite‐induced allergic airway inflammation in humanized MIF mice
H Dunbar, IJ Hawthorne, C Tunstead… - The FASEB …, 2023 - mural.maynoothuniversity.ie
Macrophage migration inhibitory factor (MIF) expression is controlled by a functional
promoter polymorphism, where the number of tetranucleotide repeats (CATTn) corresponds …
promoter polymorphism, where the number of tetranucleotide repeats (CATTn) corresponds …
Extracellular macrophage migration inhibitory factor (MIF) downregulates adipose hormone-sensitive lipase (HSL) and contributes to obesity
L Chen, L Li, D Cui, Y Huang, H Tong, H Zabihi… - Molecular …, 2024 - Elsevier
Attenuation of adipose hormone sensitive lipase (HSL) may impair lipolysis and exacerbate
obesity. We investigate the role of cytokine, macrophage migration inhibitory factor (MIF) in …
obesity. We investigate the role of cytokine, macrophage migration inhibitory factor (MIF) in …
Deficiency of MIF accentuates overloaded compression‐induced nucleus pulposus cell oxidative damage via depressing mitophagy
Y Wang, Y Hu, H Wang, N Liu, L Luo… - Oxidative Medicine …, 2021 - Wiley Online Library
Established studies proved that mechanical compression loading had multiple effects on the
biological behavior of the intervertebral disc (IVD). However, the regulating mechanism …
biological behavior of the intervertebral disc (IVD). However, the regulating mechanism …
Macrophage migration inhibitory factor (MIF) promotes intervertebral disc degeneration through the NF‐κB pathway, and the MIF inhibitor CPSI‐1306 alleviates …
Y Zhang, L Zheng, J Fang, K Ni, X Hu, L Ye… - The FASEB …, 2023 - Wiley Online Library
Lumbar intervertebral disc degeneration (IDD) is a prevalent inflammatory disease caused
by many proinflammatory factors, such as TNF and IL‐1β. Migration inhibitory factor (MIF) is …
by many proinflammatory factors, such as TNF and IL‐1β. Migration inhibitory factor (MIF) is …
Comprehensive analysis of mitophagy-related genes in diagnosis and heterogeneous endothelial cells in chronic rhinosinusitis: based on bulk and single-cell RNA …
S Zhou, K Fan, J Lai, S Tan, Z Zhang, J Li, X Xu… - Frontiers in …, 2023 - frontiersin.org
Background: Chronic rhinosinusitis (CRS) is a complex inflammatory disorder affecting the
nasal and paranasal sinuses. Mitophagy, the process of selective mitochondrial degradation …
nasal and paranasal sinuses. Mitophagy, the process of selective mitochondrial degradation …
Does Macrophage Migration Inhibitory Factor predict the prognosis of COVID-19 disease?
Introduction: The aim of this study is to investigate whether macrophage migration inhibitory
factor (MIF) predicts the prognosis of COVID-19 disease. Methodology: This descriptive and …
factor (MIF) predicts the prognosis of COVID-19 disease. Methodology: This descriptive and …