Cyclodextrins, natural compounds, and plant bioactives—a nutritional perspective

S Wüpper, K Lüersen, G Rimbach - Biomolecules, 2021 - mdpi.com
Cyclodextrins (CDs) are a group of cyclic oligosaccharides produced from starch or starch
derivatives. They contain six (αCD), seven (βCD), eight (γCD), or more glucopyranose …

A Review of Swertia chirayita (Gentianaceae) as a Traditional Medicinal Plant

V Kumar, J Van Staden - Frontiers in pharmacology, 2016 - frontiersin.org
Swertia chirayita (Gentianaceae), a popular medicinal herb indigenous to the temperate
Himalayas is used in traditional medicine to treat numerous ailments such as liver disorders …

Recent developments on the extraction and application of ursolic acid. A review

L López-Hortas, P Pérez-Larrán… - Food Research …, 2018 - Elsevier
Ursolic acid (UA) is a pentacyclic triterpenoid widely found in herbs, leaves, flowers and
fruits; update information on the major natural sources or agro-industrial wastes is …

Stable PEG-coated silver nanoparticles–A comprehensive toxicological profile

I Pinzaru, D Coricovac, C Dehelean, EA Moacă… - Food and Chemical …, 2018 - Elsevier
The present study was purported to assess the toxicological profile of bare and polyethylene
glycol (PEG) coated spherical silver nanoparticles (AgNPs) by means of in vitro (on human …

Inclusion of terpenes in cyclodextrins: Preparation, characterization and pharmacological approaches

PSS Lima, AM Lucchese, HG Araujo-Filho… - Carbohydrate …, 2016 - Elsevier
Terpenes constitute the largest class of natural products and are important resources for the
pharmaceutical, food and cosmetics industries. However, due to their low water solubility …

Ursolic acid: A systematic review of its pharmacology, toxicity and rethink on its pharmacokinetics based on PK-PD model

Q Sun, M He, M Zhang, S Zeng, L Chen, L Zhou, H Xu - Fitoterapia, 2020 - Elsevier
Ursolic acid (UA) is a natural pentacyclic triterpenoid compound existing in various
traditional Chinese medicinal herbs, and it possesses diverse pharmacological actions and …

Tubeimoside-I sensitizes temozolomide-resistant glioblastoma cells to chemotherapy by reducing MGMT expression and suppressing EGFR induced PI3K/Akt/mTOR …

Q Tang, H Cao, N Tong, Y Liu, W Wang, Y Zou, L Xu… - Phytomedicine, 2022 - Elsevier
Abstract Background Glioblastoma multiforme (GBM, World Health Organization [WHO]
grade IV) is one of the malignant Central Nerve System (CNS) tumors with high incidence …

Combination of chemotherapy and physical plasma elicits melanoma cell death via upregulation of SLC22A16

SK Sagwal, G Pasqual-Melo, Y Bodnar… - Cell Death & …, 2018 - nature.com
Malignant melanoma is an aggressive cancer that develops drug resistance leading to poor
prognosis. Efficient delivery of chemotherapeutic drugs to the tumor tissue remains a major …

Cutaneous melanoma—a long road from experimental models to clinical outcome: a review

D Coricovac, C Dehelean, EA Moaca, I Pinzaru… - International journal of …, 2018 - mdpi.com
Cutaneous melanoma is a complex disorder characterized by an elevated degree of
heterogeneity, features that place it among the most aggressive types of cancer. Although …

Biocompatible colloidal suspensions based on magnetic iron oxide nanoparticles: synthesis, characterization and toxicological profile

DE Coricovac, EA Moacă, I Pinzaru, C Cîtu… - Frontiers in …, 2017 - frontiersin.org
The use of magnetic iron oxide nanoparticles in biomedicine has evolved intensely in the
recent years due to the multiple applications of these nanomaterials, mainly in domains like …