The 2020 Focused Updates to the Asthma Management Guidelines: A Report from the
National Asthma Education and Prevention Program Coordinating Committee Expert Panel …

Executive summary Asthma is responsible for considerable global morbidity and health-care
costs. Substantial progress was made against key outcomes such as hospital admissions …

Severe and Difficult-to-Treat Asthma in Adults | NEJM Skip to main content NEJM Group Follow
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Non‐T2 asthma is traditionally defined as asthma without features of T2 asthma. The
definition is arbitrary and is generally based on the presence of neutrophils in sputum, or the …

abstract Bronchial asthma is characterized by chronic airway inflammation, which manifests
clinically as variable airway narrowing (wheezes and dyspnea) and cough. Long-standing …

Monoclonal antibodies targeting IgE or the type-2 cytokines interleukin (IL)-4, IL-5 and IL-13
are proving highly effective in reducing exacerbations and symptoms in people with severe …

Background While the complexity of flexible bronchoscopy has increased, standard options
for moderate sedation medications have not changed in three decades. There is a need to …

Evaluation and effective management of asthma, and in particular severe asthma, remains
at the core of pulmonary practice. Over the last 20–30 years, there has been increasing …

Inflammation, structural, and functional abnormalities within the airways are key features of
asthma. Although these processes are well documented, their expression varies across the …

Importance Asthma affects about 7.5% of the adult population. Evidence-based diagnosis,
monitoring, and treatment can improve functioning and quality of life in adult patients with …