Medicinal chemistry is still clearly dominated by organic chemistry. Most of the marketed
drugs are purely organic molecules. The right-hand neighbors of carbon in the periodic …

Amination of carboranes has a good application prospect in organic and pharmaceutical
synthesis. However, the current methods used for this transformation suffer from limitations …

Over the past several decades, metal-catalyzed cross-coupling has emerged as a very
powerful strategy to functionalize carbon-based molecules. More recently, some of the cross …

Transition metal catalyzed regioselective amination of the cage B (4)–H bond in o-
carboranes has been achieved for the first time using O-benzoyl hydroxylamines or organic …

200 years of research with carbon-rich molecules have shaped the development of modern
chemistry. Research pertaining to the chemistry of boron-rich species has historically trailed …

Carboranes are boron-rich molecules that can be functionalized through metal-catalyzed
cross-coupling. Here, for the first time, we report the use of bromo-carboranes in palladium …

A palladium‐catalyzed highly selective 3, 4‐bifunctionalization of 3‐I‐o‐carborane has been
developed, leading to the preparation of 3‐alkenyl‐4‐R‐o‐carboranes (R= alkyl, alkynyl …

Mefenamic acid represents a widely used nonsteroidal anti-inflammatory drug (NSAID) to
treat the pain of postoperative surgery and heavy menstrual bleeding. Like other NSAIDs …

A rhodium-catalyzed direct and regioselective amidation of the cage B (4)–H bond in a wide
range of o-carboranes with alkyl-, aryl-, and heteroaryl-substituted dioxazolones is …

Described is the Ir-catalyzed cage B (4)-amidation of o-carboranes with dioxazolones by
carboxylic acid-assisted B (4)–H bond activation under extremely mild conditions, affording …