Autonomic nervous system activity changes in patients with hypertension and overweight: role and therapeutic implications

P Valensi - Cardiovascular diabetology, 2021 - Springer
The incidence and prevalence of hypertension is increasing worldwide, with approximately
1.13 billion of people currently affected by the disease, often in association with other …

Resting heart rate and the risk of cardiovascular disease, total cancer, and all-cause mortality–a systematic review and dose–response meta-analysis of prospective …

D Aune, A Sen, B ó'Hartaigh, I Janszky… - Nutrition, Metabolism …, 2017 - Elsevier
Background and aim Epidemiological studies have reported increased risk of cardiovascular
disease, cancer and all-cause mortality with greater resting heart rate, however, the …

Obesity‐related metabolic syndrome: mechanisms of sympathetic overactivity

MP Canale, S Manca di Villahermosa… - International journal …, 2013 - Wiley Online Library
The prevalence of the metabolic syndrome has increased worldwide over the past few
years. Sympathetic nervous system overactivity is a key mechanism leading to hypertension …

Oscillatory patterns in sympathetic neural discharge and cardiovascular variables during orthostatic stimulus

R Furlan, A Porta, F Costa, J Tank, L Baker, R Schiavi… - Circulation, 2000 - Am Heart Assoc
Background—We tested the hypothesis that a common oscillatory pattern might characterize
the rhythmic discharge of muscle sympathetic nerve activity (MSNA) and the spontaneous …

Obesity and adipokines: effects on sympathetic overactivity

MM Smith, CT Minson - The Journal of physiology, 2012 - Wiley Online Library
Excess body weight is a major risk factor for cardiovascular disease, increasing the risk of
hypertension, hyperglycaemia and dyslipidaemia, recognized as the metabolic syndrome …

Glucose, obesity, metabolic syndrome, and diabetes: relevance to incidence of heart failure

TB Horwich, GC Fonarow - Journal of the American college of cardiology, 2010 - jacc.org
Heart failure (HF) is common, results in poor clinical outcomes, and is associated with large
health care costs. The incidence of HF continues to rise, with approximately 670,000 new …

The association among autonomic nervous system function, incident diabetes, and intervention arm in the Diabetes Prevention Program

MR Carnethon, RJ Prineas, M Temprosa… - Diabetes …, 2006 - Am Diabetes Assoc
OBJECTIVE—Autonomic nervous system dysfunction, a correlate of obesity and poor
cardiorespiratory fitness, is associated with the development of diabetes. We tested whether …

Influence of autonomic nervous system dysfunction on the development of type 2 diabetes: the CARDIA study

MR Carnethon, DR Jacobs Jr, S Sidney, K Liu - Diabetes care, 2003 - Am Diabetes Assoc
OBJECTIVE—We investigated whether autonomic nervous system dysfunction, estimated by
slow heart rate recovery (HRR) following cessation of an exercise treadmill test, was …

Unrecognized glucose intolerance is common in pulmonary arterial hypertension

ME Pugh, IM Robbins, TW Rice, J West… - The Journal of heart and …, 2011 - Elsevier
Background Animal and human data suggest insulin resistance is common in pulmonary
arterial hypertension (PAH). Although routine assessment of insulin resistance is difficult …

Association of fasting plasma glucose with heart rate recovery in healthy adults: a population-based study

C Panzer, MS Lauer, A Brieke, E Blackstone… - Diabetes, 2002 - Am Diabetes Assoc
Diabetes is associated with abnormal autonomic function and increased mortality. Abnormal
heart rate recovery after exercise, a measure of autonomic dysfunction, is also associated …