The immune and nervous systems have unique developmental trajectories that individually
build intricate networks of cells with highly specialized functions. These two systems have …

Arecent REVIEW in this journal'reveals that many cytokines and their receptors are
distributed widely in the PNS and the CNS, and their expression is influenced by changes in …

Background and Purpose—We tested the hypothesis that intravenous infusion of bone
marrow derived–marrow stromal cells (MSCs) enter the brain and reduce neurological …

Background and Purpose—Human umbilical cord blood cells (HUCBC) are rich in stem and
progenitor cells. In this study we tested whether intravenously infused HUCBC enter brain …

The CSF-1 receptor (CSF-1R) regulates CNS microglial development. However, the
localization and developmental roles of this receptor and its ligands, IL-34 and CSF-1, in the …

The epigenetic signals that regulate lineage development in the embryonic mammalian
brain are poorly understood. Here we demonstrate that a specific subclass of the …

Microglia cells are the major orchestrator of the brain inflammatory response. As such, they
are traditionally studied in various contexts of trauma, injury, and disease, where they are …

Neural stem cells are present both in the developing nervous system and in the adult
nervous system of all mammals, including humans. Little is known, however, about the …

Protection against pathogens is a prerequisite for survival of most organisms. To cope with
this continuous challenge, complex defense mechanisms have evolved. The construction …

We explored the association of inflammatory mediators and markers of autoimmune and
coagulation disorders with cerebral palsy (CP), examinig 53 analytes in dried neonatal …