The development of drug-resistant bacteria, as well as multidrug-resistant pathogens related
to substantial mortality, is an important global health threat. The wide range of biological …

Methicillin-resistant Staphylococcus aureus (MRSA) is becoming lethal to humanity due to
easy transmission and difficult-to-treat skin and flimsy diseases. The most threatening aspect …

The increase in antibiotic resistance due to various factors has encouraged the look for
novel compounds which are active against multidrug-resistant pathogens. In this framework …

The rise of drug-resistance has made the deserted clinical requirement to improve of new
classes of antibiotics agents. The development of antibacterial agents with the novel method …

Compounds containing an Ssingle bondF bond have garnered intense interest in the
chemical and biological literature. In particular, sulfonyl fluorides (RSO 2 F) are commonly …

Vinyl sulfone with electrophilic character is not only a versatile building block for various
organic transformations but also is a key structural unit in a large number of biologically …

The continuous demand of medicinally important scaffolds has prompted the synthetic
chemists to identify simple and efficient routes for their synthesis. 1H-1, 2, 3-triazole …

Current medicinal chemistry relies heavily on the quality of building blocks, ie reagents used
to introduce chemical diversity into the target molecules. The last decade witnessed an …

Antibacterial-resistance speaks to an overall alarm, particularly in regards to the flare-up of
methicillin-resistance Staphylococcus aureus (MRSA), a classic reason for genuine skin and …

Methicillin-resistant Staphylococcus aureus (MRSA) is becoming dangerous to human
beings due to easy transmission mode and leading to the difficult-to-treat situation. The rapid …