Neuropathic pain (NP) is pain caused by somatosensory nervous system injury or disease.
Its prominent symptoms are spontaneous pain, hyperalgesia, and allodynia, and the sense …

Background Spinal cord injury (SCI) is a serious neurological spinal cord damage that
resulted in the loss of temporary or permanent function. However, there are even now no …

Background Spinal cord injury (SCI) is an inflammatory condition, and excessive adenosine
triphosphate (ATP) is released into the extracellular space, which can be catabolized into …

Glycolysis is the metabolic pathway that converts glucose into pyruvate. Central nervous
system (CNS) pathologies, such as spinal cord injury (SCI) and ischemia, are accompanied …

Local inflammation plays a pivotal role in the process of secondary damage after spinal cord
injury. We recently reported that acute intravenous application of extracellular vesicles (EVs) …

Neurotrophic growth factor (GF) loaded hydrogels have shown promise as a treatment
approach for spinal cord injury (SCI). However, SCI presents complex challenges for the …

Abstract Background Spinal cord injuries (SCIs) can cause a loss of neurons and associated
sensory and motor functionality below the injured site. No approaches to treating SCIs in …

Cell transplantation has been an appealing way to improve the recovery of motor, sensory,
and autonomic functions following spinal cord injury (SCI). Herein, we sought to elucidate …

Peripheral nerve injury is a common injury disease. Understanding of the mechanisms of
periphery nerve repair and regeneration after injury is an essential prerequisite for treating …

The bile acid tauroursodeoxycholic acid (TUDCA) reduces cell death under oxidative stress
and inflammation. Implants of bone marrow-derived stromal cells (bmSC) are currently …