Relaxin-like peptide family exhibit differential expression patterns in various types of cancers
and play a role in cancer development. This family participates in tumorigenic processes …

Throughout the 20th Century, regulatory peptide discovery advanced from the identification
of gut hormones to the extraction and characterization of hypothalamic hypophysiotropic …

Background Peripheral biomarkers are increasingly vital non-invasive methods for
monitoring coronary artery disease (CAD) progression. Their superiority in early detection …

INSL5 and relaxin-3 are relaxin family peptides with important roles in gut and brain
function, respectively. They mediate their actions through the class A GPCRs RXFP4 and …

Little is known about the damage to the important peripheral immune organ spleen caused
by Streptococcus suis infection. In this study, we found that S. suis induced splenomegaly …

The gastrointestinal hormone, insulin-like peptide 5 (INSL5), is found in large intestinal
enteroendocrine cells (EEC). One of its functions is to stimulate nerve circuits that increase …

There is no common consensus for the physiological role of insulin-like peptide 5 (INSL5)
and its cognate receptor, relaxin family peptide receptor 4 (RXFP4). The experimental data …

Aims Insulin-like peptide 5 (INSL5) plays an important part in metabolic processes in vitro
and in vivo. We hypothesized that INSL5 levels are associated with the presence of …

Insulin-like peptide 5 (INSL5) is a novel gastrointestinal (GI) hormone, primarily expressed in
the distal colon and rectum. Its cognate receptor is the G-protein coupled receptor (GPCR) …

Relaxin family peptide receptors (RXFP, nomenclature as agreed by the NC-IUPHAR
Subcommittee on Relaxin family peptide receptors [23, 119]) may be divided into two pairs …