The Zrt‐/Irt‐like protein (ZIP) family consists of divalent metal transporters, ubiquitous in all
kingdoms of life. Since the discovery of the first ZIPs in the 1990s, the ZIP family has been …

Spermatogenesis is a cell differentiation process that ensures the production of fertilizing
sperm, which ultimately fuse with an egg to form a zygote. Normal spermatogenesis relies …

Studies of model organisms have provided important insights into how natural genetic
differences shape trait variation. These discoveries are driven by the growing availability of …

The trace element zinc is essential for many aspects of physiology. The mitochondrion is a
major Zn2+ store, and excessive mitochondrial Zn2+ is linked to neurodegeneration. How …

Abstract The Zrt-/Irt-like protein (ZIP) family consists of ubiquitously expressed divalent metal
transporters critically involved in maintaining systemic and cellular homeostasis of zinc, iron …

Mating systems have profound effects on genetic diversity and compatibility. The convergent
evolution of self-fertilization in three Caenorhabditis species provides a powerful lens to …

The polyandrous mating system of honeybees (Apis mellifera L.) has garnered widespread
attention. Long-lived honeybee queens only mate early in maturation, and the sperm …

Zinc is an essential trace element that acts as a co-factor for many enzymes and
transcription factors required for cellular growth and development. Altering intracellular zinc …

It is estimated that up to 10% of proteins in eukaryotes require zinc for their function.
Although the majority of these proteins are located in the nucleus and cytosol, a small subset …

Apoptotic death of cells damaged by genotoxic stress requires regulatory input from
surrounding tissues. The C. elegans scaffold protein KRI-1, ortholog of mammalian …