Wet granulation is a key step in the pharmaceutical manufacturing of solid-dosage forms.
Wet granulation is used in pharmaceutical production to enhance formulation qualities such …

Wet granulation is a very important unit operation that finds applications in many industries
mainly pharmaceutical and chemical industries. Various granulation technologies in batch …

Abstract In Discrete Element Method (DEM) simulations, particle–particle contact laws
determine the macroscopic simulation results. Particle-based contact laws, in turn …

Continuous crystallization has always been a hot topic in industrial crystallization. Many
efforts have been made to improve the continuous crystallization, either by designing novel …

High shear wet granulation (HSWG) is considered a complicated and multivariate
pharmaceutical process that is influenced by a large number of variables derived from …

The computational cost of the discrete element method (DEM)-population balance model
(PBM) coupled framework is predominantly attributed to DEM simulations. To overcome this …

Computational modelling of twin-screw granulation was conducted by using an artificial
neural network (ANN) approach. Various ANN configurations were considered with …

A correlation-based model order reduction algorithm is developed using support vector
machine to model NO x emission and break mean effective pressure of a medium-duty …

In this study, a novel mechanistic model for a wet granulation process is presented,
combining the techniques of population balance modeling and discrete element methods to …

Vibrating screens are widely used in industry but it is difficult to consider the enormous
controlling variables and complicated particle-particle interactions in current screen process …