Imaging of the optic nerve: technological advances and future prospects

V Biousse, HV Danesh-Meyer, AM Saindane… - The Lancet …, 2022 - thelancet.com
Over the past decade, ocular imaging strategies have greatly advanced the diagnosis and
follow-up of patients with optic neuropathies. Developments in optic nerve imaging have …

Recent advances and future directions on the use of optical coherence tomography in neuro-ophthalmology

C Lo, LN Vuong, JA Micieli - Taiwan Journal of Ophthalmology, 2021 - journals.lww.com
Optical coherence tomography (OCT) is a noninvasive imaging technique used to
qualitatively and quantitatively analyze various layers of the retina. OCT of the retinal nerve …

[HTML][HTML] Can deep learning revolutionize clinical understanding and diagnosis of optic neuropathy?

MD Subramaniam, A Kumar, RB Chirayath… - Artificial Intelligence in …, 2021 - Elsevier
Artificial intelligence (AI) based on deep learning (DL) has sparked tremendous global
interest in recent years. Deep Learning has been widely adopted in speech and image …

Mitochondrial retinopathies and optic neuropathies: the impact of retinal imaging on modern understanding of pathogenesis, diagnosis, and management

E Borrelli, F Bandello, CJF Boon, V Carelli… - Progress in Retinal and …, 2024 - Elsevier
Advancements in ocular imaging have significantly broadened our comprehension of
mitochondrial retinopathies and optic neuropathies by examining the structural and …

Leber's hereditary optic neuropathy: current approaches and future perspectives on Mesenchymal stem cell-mediated rescue

SM Devi, BA Kumar, I Mahalaxmi, V Balachandar - Mitochondrion, 2021 - Elsevier
Abstract Leber's Hereditary Optic Neuropathy (LHON) is an inherited optic nerve disorder. It
is a mitochondrially inherited disease due to point mutation in the MT-ND1, MT-ND4, and MT …

Age‐dependent retinal neuroaxonal degeneration in children and adolescents with Leber hereditary optic neuropathy under idebenone therapy

B Schworm, J Siedlecki, C Catarino… - European Journal of …, 2023 - Wiley Online Library
Background The aim of this study was to investigate the neuroretinal structure of young
patients with Leber hereditary optic neuropathy (LHON). Methods For this retrospective …

Choroidal vascularity index in hereditary optic neuropathies

M Battista, ML Cascavilla, E Borrelli, C Barresi, G Lari… - Eye, 2023 - nature.com
Purpose To assess the choroidal vascularity index (CVI) in patients affected by Leber
hereditary optic neuropathy (LHON) compared to patients affected by dominant optic atrophy …

Observation of peripapillary choroidal vascularity in natural disease course and after gene therapy for Leber's hereditary optic neuropathy

J Jiang, G Sun, Q Miao, B Li, D Wang, J Yuan… - Frontiers in …, 2021 - frontiersin.org
Purpose: To compare peripapillary choroidal vascularity among Leber's Hereditary Optic
Neuropathy (LHON) patients at different stages of natural course and healthy controls using …

Choroidal thickness in eyes with band atrophy of the optic nerve from chiasmal compression

LGM Mello, ACF Suzuki, GR de Mello… - Journal of …, 2022 - Wiley Online Library
Background. The choroid is a vascular tissue that helps maintain retinal and prelaminar
optic nerve head function. Choroidal thickness has been previously studied in diseases …

Choriocapillaris and choroidal thickness in all Leber hereditary optic neuropathy stages using swept source technology

L Castillo, C Berrozpe‐Villabona… - Acta …, 2024 - Wiley Online Library
Purpose The role of the choroid in Leber hereditary optic neuropathy (LHON) remains
unclear. The literature is scarce, with conflicting results and lacks axial length …