Current strategies for exosome cargo loading and targeting delivery
Extracellular vesicles (EVs) such as ectosomes and exosomes have gained attention as
promising natural carriers for drug delivery. Exosomes, which range from 30 to 100 nm in …
promising natural carriers for drug delivery. Exosomes, which range from 30 to 100 nm in …
Manufactured extracellular vesicles as human therapeutics: challenges, advances, and opportunities
Highlights•EVs come in two classes: native or engineered with defined therapeutic
entity.•Advances in engineering EVs to load cargo have enhanced potency.•High-density …
entity.•Advances in engineering EVs to load cargo have enhanced potency.•High-density …
Milk-derived extracellular vesicles protect intestinal barrier integrity in the gut-liver axis
Milk-derived extracellular vesicles (mEVs) have been proposed as a potential nanomedicine
for intestinal disorders; however, their impact on intestinal barrier integrity in gut …
for intestinal disorders; however, their impact on intestinal barrier integrity in gut …
Rejuvenation of tendon stem/progenitor cells for functional tendon regeneration through platelet-derived exosomes loaded with recombinant Yap1
J Lu, X Yang, C He, Y Chen, C Li, S Li, Y Chen, Y Wu… - Acta Biomaterialia, 2023 - Elsevier
The regenerative capabilities including self-renewal, migration and differentiation potentials
shift from the embryonic phase to the mature period of endogenous tendon stem/progenitor …
shift from the embryonic phase to the mature period of endogenous tendon stem/progenitor …
Antibody-displaying extracellular vesicles for targeted cancer therapy
Extracellular vesicles (EVs) function as natural delivery vectors and mediators of biological
signals across tissues. Here, by leveraging these functionalities, we show that EVs …
signals across tissues. Here, by leveraging these functionalities, we show that EVs …
Purposing plant-derived exosomes-like nanovesicles for drug delivery: Patents and literature review
NS Orefice, R Di Raimo, D Mizzoni… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction How can biotechnology and organic agriculture be fused and promoted
simultaneously to overcome the main challenges in drug delivery systems. The role of …
simultaneously to overcome the main challenges in drug delivery systems. The role of …
Engineering of MSC-derived exosomes: a promising cell-free therapy for osteoarthritis
J Cheng, Y Sun, Y Ma, Y Ao, X Hu, Q Meng - Membranes, 2022 - mdpi.com
Osteoarthritis (OA) is characterized by progressive cartilage degeneration with increasing
prevalence and unsatisfactory treatment efficacy. Exosomes derived from mesenchymal …
prevalence and unsatisfactory treatment efficacy. Exosomes derived from mesenchymal …
Extracellular vesicles as drug transporters
M Nowak, J Górczyńska, K Kołodzińska… - International Journal of …, 2023 - mdpi.com
Extracellular vesicles (EVs) are lipid bilayer-delimited particles. According to their size and
synthesis pathway, EVs can be classified into exosomes, ectosomes (microvesicles), and …
synthesis pathway, EVs can be classified into exosomes, ectosomes (microvesicles), and …
Unveiling the Yin-Yang Balance of M1 and M2 Macrophages in Hepatocellular Carcinoma: Role of Exosomes in Tumor Microenvironment and Immune Modulation
Hepatocellular carcinoma (HCC) is a primary liver cancer with a high mortality rate and
limited treatment options. Recent research has brought attention to the significant …
limited treatment options. Recent research has brought attention to the significant …
Liposomes or extracellular vesicles: a comprehensive comparison of both lipid bilayer vesicles for pulmonary drug delivery
The rapid and non-invasive pulmonary drug delivery (PDD) has attracted great attention
compared to the other routes. However, nanoparticle platforms, like liposomes (LPs) and …
compared to the other routes. However, nanoparticle platforms, like liposomes (LPs) and …