Microtubules are one of the major cytoskeletal components of neurons, essential for many
fundamental cellular and developmental processes, such as neuronal migration, polarity …

Neurons are terminally differentiated cells that use their microtubule arrays not for cell
division but rather as architectural elements required for the elaboration of elongated axons …

Over the past several decades, numerous studies have greatly expanded our knowledge
about how microtubule organization and dynamics are controlled in cultured cells in vitro …

Mitochondria are multifunctional organelles that not only produce energy for the cell, but are
also important for cell signalling, apoptosis and many biosynthetic pathways. In most cell …

The MAP kinase and motor scaffold JIP3 prevents excess lysosome accumulation in axons
of vertebrates and invertebrates. How JIP3's interaction with dynein and kinesin-1 …

In cultured vertebrate neurons, axons have a uniform arrangement of microtubules with plus-
ends distal to the cell body (plus-end-out), whereas dendrites contain mixed polarity …

Proper brain wiring during development is pivotal for adult brain function. Neurons display a
high degree of polarization both morphologically and functionally, and this polarization …

Axonal microtubule (MT) arrays are the major cytoskeleton substrate for cargo transport.
How MT organization, ie, polymer length, number, and minus-end spacing, is regulated and …

Highlights•Regulation of non-centrosomal microtubule organization in neurons.•Role of
resilient acetylated microtubules in mechanosensation.•Patterning microtubule tracks to …

Trafficking of mitochondria into dendrites and axons plays an important role in the
physiology and pathophysiology of neurons. Mitochondrial outer membrane protein Miro …