Technetium (I) carbonyl complexes for nuclear medicine: Coordination-chemical aspect

GV Sidorenko, AE Miroslavov, MY Tyupina - Coordination Chemistry …, 2023 - Elsevier
Studies concerning the development of radiopharmaceuticals based on the Tc (I) carbonyl
core are considered from the coordination-chemical viewpoint. The coordination behavior of …

Bioorganometallics: 99mTc cytectrenes, syntheses and applications in nuclear medicine

R Lengacher, R Alberto - Coordination Chemistry Reviews, 2021 - Elsevier
Abstract 99m Tc is one of the most frequently used isotopes in medicinal nuclear imaging.
The two parts of this review summarize the chemistry of 99m Tc-cytectrenes of the type [η 5 …

16-Cyclopentadienyl Tricarbonyl 99mTc 16-Oxo-hexadecanoic Acid: Synthesis and Evaluation of Fatty Acid Metabolism in Mouse Myocardium

BC Lee, DH Kim, I Lee, YS Choe, DY Chi… - Journal of medicinal …, 2008 - ACS Publications
We synthesized 16-cyclopentadienyl tricarbonyl 99mTc 16-oxo-hexadecanoic acid (99mTc-
CpTT-16-oxo-HDA, 1) and investigated its potential as a radiotracer for evaluating fatty acid …

Synthesis and biological evaluation of RGD peptides with the 99m Tc/188 Re chelated iminodiacetate core: Highly enhanced uptake and excretion kinetics of …

BC Lee, BS Moon, JS Kim, JH Jung, HS Park… - RSC Advances, 2013 - pubs.rsc.org
To develop a companion set of RGD-based agents for diagnostic and radiotherapeutic
purposes, facile incorporation of 99mTc (CO) 3 or 188Re (CO) 3 into the same precursor …

Synthesis and Evaluation of Tricarbonyl 99mTc-Labeled 2-(4-Chloro)phenyl-imidazo[1,2-a]pyridine Analogs as Novel SPECT Imaging Radiotracer for TSPO-Rich …

JY Choi, RM Iacobazzi, M Perrone, N Margiotta… - International journal of …, 2016 - mdpi.com
The 18-kDa translocator protein (TSPO) levels are associated with brain, breast, and
prostate cancer progression and have emerged as viable targets for cancer therapy and …

Synthesis and biological evaluation of fatty acids conjugates bearing cyclopentadienyl-donors incorporated [99mTc/Re (CO) 3]+ for myocardical imaging

H Zeng, H Zhang - European Journal of Medicinal Chemistry, 2014 - Elsevier
Four 99m Tc-labeled fatty acid analogs, 1b, 2b, 3b, 4b were synthesized by a double ligand
transfer reaction and theirs potential were investigated. The radiochemical yield of the …

Metal complexes containing natural and artificial radioactive elements and their applications

OV Kharissova, MA Méndez-Rojas, BI Kharisov… - Molecules, 2014 - mdpi.com
Recent advances (during the 2007–2014 period) in the coordination and organometallic
chemistry of compounds containing natural and artificially prepared radionuclides (actinides …

“2+1” Rhenium and Technetium Tricarbonyl Complexes with N,N′-Bidentate Ligands and Methyl 11-Isocyanoundecanoate

AE Miroslavov, AP Sakhonenkova, MY Tyupina… - Russian Journal of …, 2023 - Springer
Abstract “2+ 1” tricarbonyl compexes [M (CO) 3 (N^ N) CN (CH2) 10COOMe] ClO4, where
M= Tc or Re, N^ N= 2, 2′-bipyridine (bipy) or 1, 10-phenanthroline (phen), were prepared …

Preliminary studies of a novel cyclopentadienyl tricarbonyl technetium‐99m fatty acid derivative for myocardical imaging

H Zeng, H Zhang, X Wu, F Chao, G Yu… - Journal of Labelled …, 2013 - Wiley Online Library
This study reports the synthesis and evaluation studies of 6′‐cyclopentadienyl tricarbonyl
technetium‐99m 6′‐oxo‐11‐(hexanamide) undecanoic acid (1). 1 was prepared with …

99mTc Radiopharmaceutical Chemistry

D Papagiannopoulou - Handbook of Radiopharmaceuticals …, 2020 - Wiley Online Library
In this chapter, the bibliography has been surveyed from 2000 to the present, and the 99mTc‐
labelled imaging agents developed are summarized. In these years, new 99mTc‐labelling …